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Eosinophilic esophagitis: updated consensus recommendations for children and adults.
Eosinophilic esophagitis (EoE) is a clinicopathologic condition of increasing recognition and prevalence. In 2007, a consensus recommendation provided clinical and histopathologic guidance for theExpand
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Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis.
Eosinophilic esophagitis (EE) is an emerging disorder with a poorly understood pathogenesis. In order to define disease mechanisms, we took an empirical approach analyzing esophageal tissue by aExpand
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Quantity and Distribution of Eosinophils in the Gastrointestinal Tract of Children
There are a lack of data on the quantity and location of eosinophils in the gastrointestinal tract of healthy individuals. Accordingly, we examined gastrointestinal biopsies obtained duringExpand
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Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses
Periostin is an extracellular matrix protein that has been primarily studied in the context of the heart, where it has been shown to promote cardiac repair and remodeling. In this study, we focusedExpand
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The spectrum of pediatric eosinophilic esophagitis beyond infancy: a clinical series of 30 children
OBJECTIVES:Eosinophilic esophagitis, previously confused with esophageal inflammation due to gastroesophageal reflux, has recently begun to be distinguished from it. We undertook this analysis of ourExpand
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A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis.
BACKGROUND & AIMS Eosinophilic esophagitis is an increasingly recognized disorder with distinctive endoscopic, histologic, and allergic features. Although several therapies are advocated, noExpand
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Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis
The desmosomal cadherin desmoglein-1 (DSG1) is an essential intercellular adhesion molecule that is altered in various human cutaneous disorders; however, its regulation and function in allergicExpand
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IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids.
BACKGROUND Eosinophilic esophagitis (EE) is an emerging worldwide disease that mimics gastroesophageal reflux disease. Early studies have established that esophageal eosinophilia occurs inExpand
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Eosinophilic esophagitis.
Purpose of review Previously perceived as an anomaly, eosinophilic esophagitis is now frequently diagnosed by both pediatric and adult specialists including gastroenterologists, allergists,Expand
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A striking local esophageal cytokine expression profile in eosinophilic esophagitis.
BACKGROUND Eosinophilic esophagitis (EE) is an emerging worldwide disease that mimics gastroesophageal reflux disease. OBJECTIVE Early studies have suggested that esophageal eosinophilia occurs inExpand
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