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Endotoxemia Is Associated With an Increased Risk of Incident Diabetes
TLDR
Both prevalent and incident diabetes were associated with endotoxemia, which may link metabolic disorders to inflammation, and the results suggest that microbes play a role in the pathogenesis of diabetes. Expand
Periodontitis decreases the antiatherogenic potency of high density lipoprotein Published, JLR Papers in Press, September 16, 2003. DOI 10.1194/jlr.M300250-JLR200
TLDR
It is suggested thatperiodontitis causes similar, but milder, changes in HDL metabolism than those that occur during the acute-phase response and that periodontitis may diminish the antiatherogenic potency of HDL, thus increasing the risk for CHD. Expand
Severe Periodontitis Enhances Macrophage Activation via Increased Serum Lipopolysaccharide
TLDR
The results suggest that in systemically healthy patients, the infected/inflamed area in periodontitis is associated with macrophage activation via increased serum LPS concentration. Expand
Serum microbial- and host-derived markers of periodontal diseases: a review.
TLDR
Serum markers of periodontitis that have been used for research purposes and/or to support diagnostics are described and discussed and research and development of serum screening methods for periodontococcal infection are encouraged. Expand
Antibodies to Periodontal Pathogens and Stroke Risk
TLDR
Serological evidence is provided that an infection caused by major periodontal pathogens is associated with future stroke in a case–control study in Finland. Expand
Analysis of matrix metalloproteinases, especially MMP-8, in gingival creviclular fluid, mouthrinse and saliva for monitoring periodontal diseases.
TLDR
Matrix metalloproteinase-8 can be used alone or together with interleukin-1beta and Porphyromonas gingivalis to calculate cumulative risk score at the subject level as a successful diagnostic tool, especially in large-scale public health surveys, in which a thorough periodontal examination is not feasible. Expand
Endotoxemia, Immune Response to Periodontal Pathogens, and Systemic Inflammation Associate With Incident Cardiovascular Disease Events
TLDR
Exposure to periodontal pathogens or endotoxin induces systemic inflammation leading to increased risk for CVD, and these associations were abolished after adjusting for serum lipids. Expand
High serum antibody levels to Porphyromonas gingivalis predict myocardial infarction
TLDR
Serological evidence is provided that an infection caused by the periodontal pathogen, P. gingivalis, increases the risk for myocardial infarction independently of classical cardiovascular risk factors. Expand
Salivary interleukin-1beta concentration and the presence of multiple pathogens in periodontitis.
TLDR
Salivary IL-1beta and the presence of multiple periodontal pathogens were associated with periodontitis at the same magnitude, when they were in the logistic regression model individually or together. Expand
Salivary MMP-8, TIMP-1, and ICTP as markers of advanced periodontitis.
TLDR
Salivary MMP-8, TIMP-1, ICTP, and especially their ratios and combinations are potential candidates in the detection of advanced periodontitis. Expand
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