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(6,7-Dimethoxy-4-methylisoquinolinyl)-(4’-methoxyphenyl)-methanone, a New Benzylisoquinoline Alkaloid from Beilschmiedia brevipes
The leaves of Beilschmiedia brevipes provided a new benzylisoquinoline alkaloid: (6,7-dimethoxy-4-methylisoquinolinyl)-(4’-methoxyphenyl)-methanone (1) and O,O-dimethylannocherin A (2), a new naturalExpand
Design and Synthesis of Chalcone Derivatives as Inhibitors of the Ferredoxin — Ferredoxin-NADP+ Reductase Interaction of Plasmodium falciparum: Pursuing New Antimalarial Agents
Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP+ reductase interaction to pursue a new selective antimalariaExpand
Inhibitory Activity and Docking Analysis of Antimalarial Agents from Stemona sp. toward Ferredoxin-NADP+ Reductase from Malaria Parasites
Ferredoxin-NADP+ reductases (FNRs, EC were found in the plastids of Plasmodium and have been considered as a target for the development of new antimalarial agents. Croomine, epi-croomine,Expand
Alkaloids from the roots of Stemona javanica (Kunth) Engl. (Stemonaceae) and their anti-malarial, acetylcholinesterase inhibitory and cytotoxic activities
Abstract Two new protostemonine-type alkaloids, javastemonine A and B ( 3 and 4 ) have been isolated from the root extracts of Stemona javanica together with four known Stemona alkaloids,Expand
Isolation of tuberospironine A, a novel croomine derivative from Stemona tuberosa Lour.
Abstract A novel croomine derivative, tuberospironine A (3- epi -tuberospironine) was isolated from the root extracts of Stemona tuberosa Lour. found growing on Seram Island, Moluccas Province,Expand
Antimalarial and antioxidant activity of phenolic compoundsisolated from Erythrina crista-galli L.
Threephenolic compounds, phaseollidin (1), sandwicensin (2), and lonchocarpol A (3) had been isolated from the stem bark of Erythrina crista-galli. Their structures were established on the basis ofExpand
RETRACTED: Novel drug delivery carrier from alginate-carrageenan and glycerol as plasticizer
Abstract Drug delivery carriers are materials that can be used to administer drugs into the human body. Alginate and carrageenan are natural polymers that have potential as drug delivery material.Expand
First Order Kinetics of Salicylamide Release from κ-Carrageenan Hard Shell Capsules in Comparison with Gelatin
Drug delivery material is one of popular topics of research in this era because the developmet of medicines require a good carrier of the drugs produced and synthesized. However, recent producedExpand
Epi -croomine and croomine from Stemona tuberosa antimalarial drug for inhibiting dihydrofolate reductase (DHFR) activity and their molecular modeling
One of the mechanism actions of antimalarial drugsi s by an inhibiting on the enzyme dihydrofolate redu ctase (DHFR), an enzyme target antifolate drug. Epi-croom ine and croomine , are alkaloidsExpand
Characterization of Alginate from Sargassum duplicatum and the Antioxidant Effect of Alginate–Okra Fruit Extracts Combination for Wound Healing on Diabetic Mice
Diabetes mellitus is a group of metabolic disorders characterized by high blood-glucose levels over a prolonged period that causes complications when an open wound is present. Alginate is anExpand