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Oxyresveratrol from Artocarpus lakoocha Roxb. Inhibit Melanogenesis in B16 Melanoma Cells through the Role of Cellular Oxidants
Overproduction of melanin pigment is well recognized in hyperpigmentation disorders and melanoma progression. In this study, we investigated the anti-oxidant activity of oxyresveratrol fromExpand
Prognostic significance of skin and subcutaneous fat sequestration of parasites in severe falciparum malaria.
Intradermal blood smear, histopathologic and immunohistologic studies were performed in severe malaria (n=10) and uncomplicated malaria (n=10) patients during positive parasitemia and within 6 hoursExpand
Identification and characterization of protein 14-3-3 in carcinogenic liver fluke Opisthorchis viverrini.
Protein 14-3-3s are abundant phospho-serine/threonine binding proteins, which are highly conserved among eukaryotes. Members of this protein family mediate metabolism and signal transduction networksExpand
Immunohistochemical determination of estrogen and progesterone receptors in canine mammary tumors.
Mammary gland tumors are by far the most commonly found tumors in domestic dogs. Effective therapeutic procedures with prompt accurate diagnoses are of prime importance for this life threateningExpand
Anti-Aging Activity and Non-Toxic Dose of Phytooxyresveratrol from Artocarpus lakoocha Roxb
Purpose: To determine the anti-aging activity and toxicity doses of phytooxyresveratrol extracted from Artocarpus lakoocha Roxb. Methods: Artocarpus lakoocha 100 g was extracted with 2 ml of 95 %Expand
Binding capacity of ER-α ligands and SERMs: comparison of the human, dog and cat.
The estrogen molecule is the major risk factor related to mammary gland tumors, with estrogen receptor alpha (ER- α) as the important target stimulating growth. Therefore one alternative approach toExpand
The Effects of Cleistanthoside A Tetraacetate Synthesis on Acute Toxicity and Bone Marrow Micronucleus in ICR Mice
Phyllanthus taxodiifolius Beille is used in traditional medicine in tropical and subtropical areas. Although it has been used as a folk medicine for a long time, studies on its safety have beenExpand
Evaluation of genotoxic and anti-mutagenic properties of cleistanthin A and cleistanthoside A tetraacetate.
Cleistanthin A (CleinA) and cleistanthoside A (CleisA) isolated from plant Phyllanthus taxodiifolius Beille have previously shown potent anticancer effects. To promote their medicinal benefits,Expand
Effect of single mutagenesis on the binding pocket of canine estrogen receptor alpha: Structure and binding affinity
Hormone-related mammary gland tumors are among the most commonly diagnosed neoplasms in female dogs. Estrogen enacts its biological roles through specific receptors known as estrogen receptors (ER).Expand
AE1/AE3, vimentin and p63 immunolocalization in canine mammary gland tumours: roles in differentiation between luminal epithelial and myoepithelial lineages.
Mammary tumors are by far the most common tumors in female dogs and effective treatment relies on prompt and accurate diagnostic procedures. Canine mammary tumors may originate from various cellExpand