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Malignancy in coeliac disease--effect of a gluten free diet.
TLDR
The results indicate that for coeliac patients who have taken a GFD for five years or more the risk of developing cancer over all sites is not increased when compared with the general population, and give further support for advising all patients to adhere to a strict G FD for life.
Ulcerative colitis and Crohn's disease: a comparison of the colorectal cancer risk in extensive colitis.
TLDR
There was an 18-fold increase in the risk of developing colorectal cancer in extensive Crohn's colitis and a 19-fold increased in risk in extensive ulcerative colitis when compared with the general population, matched for age, sex, and years at risk.
Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres.
TLDR
It is suggested that extensive colitis patients have a genetic predisposition to colorectal cancer and that longstanding inflammation is not of primary importance in the initiation/promotion of cancer in this disease.
Radiation dose and second cancer risk in patients treated for cancer of the cervix.
TLDR
Risks were highest among long-term survivors and appeared concentrated among women irradiated at relatively younger ages, and radiation was not found to increase the overall risk of cancers of the small intestine, colon, ovary, vulva, connective tissue, breast, Hodgkin's disease, multiple myeloma, or chronic lymphocytic leukemia.
Radiation dose and leukemia risk in patients treated for cancer of the cervix.
TLDR
The model proposed in this study of risk proportional to mass exposed and of risk to an individual given by the sum of incremental risks to anatomic sites appears to be applicable to a wide range of dose distributions.
Malignancy in Crohn's disease.
TLDR
Cancer morbidity has been evaluated in a series of 513 patients with Crohn's disease under long-term review between 1944-76 and there was no excess of tumours at any site outside the digestive system.
Cause of death in rheumatoid arthritis.
TLDR
A series of 489 consecutive patients with definite or classical rheumatoid arthritis was followed for a mean of 11.2 years, showing a three-fold increase in mortality overall in comparison with age- and sex-specific rates in the general population.
Longterm mortality outcome in patients with rheumatoid arthritis: early presenters continue to do well.
TLDR
Patients with RA should be referred early, and those with chronic disease should be closely monitored for evidence of infection and renal impairment, as SMR due to infection, renal failure, and non-Hodgkin's lymphoma rose with disease duration.
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