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Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment.
This study adopts a combined computational and experimental approach to determine the mechanical, structural, and metabolic properties of isolated chondrocytes cultured within three-dimensional… Expand
Bardet–Biedl syndrome proteins control the cilia length through regulation of actin polymerization
- Victor Hernandez-Hernandez, P. Pravincumar, +4 authors P. Beales
- Biology, Medicine
- Human molecular genetics
- 27 May 2013
Primary cilia are cellular appendages important for signal transduction and sensing the environment. Bardet–Biedl syndrome proteins form a complex that is important for several cytoskeleton-related… Expand
Viscoelastic Cell Mechanics and Actin Remodelling Are Dependent on the Rate of Applied Pressure
Background Living cells are subjected to external and internal mechanical stresses. The effects of these stresses on the deformation and subsequent biological response of the cells remains unclear.… Expand
Bardet-Biedl syndrome proteins control cilia length through regulation of actin polymerisation
Primary cilia are cellular appendages important for signal transduction and sensing the environment. Bardet-Biedl syndrome proteins form a complex that is important for several cytoskeleton-related… Expand
PRESSURE RATE SENSITIVE VISCOELASTIC CELL DEFORMATION INVOLVES ACTIN REMODELLING