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Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma
TLDR
It is suggested that early life events may permanently impact on the HPA axis though epigenetic modifications of the NR3C1, a mechanism by which childhood maltreatment may lead to adulthood psychopathology. Expand
Response to psychotherapy in borderline personality disorder and methylation status of the BDNF gene
TLDR
A relationship between child maltreatment and higher DNA methylation of BDNF is found and the idea that these epigenetic marks may be changed through psychotherapeutic approaches and that these changes underline changes in cognitive functions is supported. Expand
Distinguishing borderline personality disorder from adult attention deficit/hyperactivity disorder: A clinical and dimensional perspective
TLDR
Investigation of differences in the expression of impulsivity, anger and aggression, quality of life as well as the number and severity of the comorbidities between ADHD, BPD,Comorbid BPD-ADHD and control subjects showed high levels of impulsiveness and aggression. Expand
Comorbidity between attention deficit hyperactivity disorder (ADHD) and bipolar disorder in a specialized mood disorders outpatient clinic.
TLDR
The comorbidity of the two disorders was associated with worse outcomes, possibly resulting from stressful early-life events, and more than 40% of the subjects who scored positively at the ASRS-v1.1 did not suffer from ADHD, which suggests that this scale should be used with caution in BD subjects. Expand
Attention-related EEG markers in adult ADHD
TLDR
The reduced activation of the functional networks devoted to bottom-up and top-down attention suggests that adult ADHD patients engage reduced cortical resources in this composite task, compatible with the cortical hypoarousal model. Expand
EMOTEO: A Smartphone Application for Monitoring and Reducing Aversive Tension in Borderline Personality Disorder Patients, a Pilot Study
TLDR
A smartphone application developed to help borderline personality disorder (BPD) patients to monitor and regulate their inner tension, EMOTEO was user-friendly and efficient in reducing aversive tension in BPD patients. Expand
METHYLATION OF SEROTONIN RECEPTOR 3A IN ADHD, BORDERLINE PERSONALITY, AND BIPOLAR DISORDERS: LINK WITH SEVERITY OF THE DISORDERS AND CHILDHOOD MALTREATMENT
TLDR
The impact of childhood maltreatment on the methylation status of the 5‐HT3AR and its association with clinical severity outcomes in relation with a functional genetic polymorphism is studied. Expand
Borderline personality disorder and childhood maltreatment: A genome-wide methylation analysis
Early life adversity plays a critical role in the emergence of borderline personality disorder (BPD) and this could occur through epigenetic programming. In this perspective, we aimed to determineExpand
Psychometric Properties and Factor Structure of the Short Form of the Affective Lability Scale in Adult Patients With ADHD
TLDR
ALS-18 showed good psychometric properties in ADHD adult patients, allowing the implementation of ALS-18 in assessing affective lability for clinical and research purposes and should improve the clinical assessment of affectiveLability in adult ADHD patients. Expand
Borderline personality disorder and childhood maltreatment: a genome‐wide methylation analysis
TLDR
The results highlight the potentially important role played by miRNAs in the etiology of neuropsychiatric disorders such as BPD and the usefulness of using methylome‐wide association studies to uncover such candidate genes. Expand
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