• Publications
  • Influence
Cholesterol gallstone disease
TLDR
The physical-chemical mechanisms of gallstone formation in bile and the active role of the gallbladder and the intestine are discussed, and gaps in knowledge of the pathogenesis of gallstones formation and the potential for gene targeting in therapy are discussed. Expand
Methodology and Indications of H2‐Breath Testing in Gastrointestinal Diseases: the Rome Consensus Conference
TLDR
The final statements, graded according to the level of evidence and strength of recommendation, identify the indications for the use of H2-breath testing in the clinical practice and methods to be used for performing the tests. Expand
Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis.
TLDR
This review mechanistically focused on oxidative stress events leading to individual disease factor appearance in metabolic syndrome patients and their setting for a more helpful clinical approach. Expand
Does Mediastinal Extension of the Goiter Increase Morbidity of Total Thyroidectomy? A Multicenter Study of 19,662 Patients
TLDR
Symptoms, malignancy, overall morbidity, hypoparathyroidism, RLN palsies, phrenic nerve palsy, seroma/hematoma, and hematoma are increased in cases of substernal goiter. Expand
Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial.
TLDR
Treatment with RA but not P for 12 months was associated with improvement in liver enzymes, insulin resistance, and liver histology, without increases in body weight, and these findings warrant further investigation. Expand
Role of mitochondria in nonalcoholic fatty liver disease--from origin to propagation.
TLDR
The role of mitochondrial dysfunction in critical initiating or propagating events in fatty liver infiltration and nonalcoholic fatty liver disease (NAFLD) is examined and mitochondrial metabolic remodeling is a predominant factor in the appearance and perpetuation of hepatocyte fat accumulation. Expand
Mitochondrial dysfunction in rat with nonalcoholic fatty liver Involvement of complex I, reactive oxygen species and cardiolipin.
TLDR
It is concluded that CD diet causes mitochondrial complex I dysfunction which can be attributed to ROS-induced cardiolipin oxidation, and new insights are provided into the alterations underlying mitochondrial dysfunction in NAFLD. Expand
New insights into the molecular mechanism of intestinal fatty acid absorption
TLDR
Dietary fat, stored as triacylglycerols in the body, are an important reservoir of stored energy and derived primarily from animal fats and vegetable oils. Expand
Oxidative stress in symptom‐free HCV carriers: relation with ALT flare‐up
TLDR
The aim of this study was to assess the oxidative balance in patients with normal aminotransferase activity and to evaluate its possible role on the severity of disease. Expand
Biochemical mechanisms in drug-induced liver injury: certainties and doubts.
TLDR
Current knowledge of the mechanisms of drug-induced liver injury and recent advances on newly discovered mechanisms of liver damage are reviewed and future perspectives including new frontiers for research are discussed. Expand
...
1
2
3
4
5
...