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Prognostic value of lymphovascular space invasion determined with hematoxylin-eosin staining in early stage cervical carcinoma: results of a multivariate analysis.
TLDR
Results suggest that improvement is needed in the treatment of patients with a small tumor and LVS invasion, as LVSI represents an unfavorable prognostic factor in univariate and multivariate analyses.
Inhaled formoterol in the prevention of exercise-induced bronchoconstriction in asthmatic children.
TLDR
The protection against EIB is significantly more prolonged after formoterol than after salbutamol, and persists for 12 h after dosing, and the evaluation of the mean percentage decrease in FEV1 confirmed the results in favor offormoterol in both the exercise tests.
Counteraction on experimentally induced diabetic neuropathy by levocarnitine acetyl.
TLDR
A beneficial effect of levocarnitine acetyl on peripheral neuropathy and muscle performance is suggested and the concomitantly reduced motor performance is improved.
Design, synthesis, and structure-activity relationship of N-arylnaphthylamine derivatives as amyloid aggregation inhibitors.
TLDR
The most potent compound of this series, 4k, showed micromolar activity in this test, and could be developed to find novel potent antiaggregating βA agents useful in Alzheimer disease as well as other neurological diseases characterized by deposits of amyloid aggregates.
2-Aminotetraline Derivative Protects from Ischemia/Reperfusion Brain Injury with a Broad Therapeutic Window
TLDR
Binding data and experiments on microglial cell cultures indicate that the anti-inflammatory effect of ST1942 may be due to its action on 5-HT2B receptors, thus highlighting the possibility that this 5- HT receptor subtype may represent a novel target for neuroprotective drugs in ischemic injury.
Severity of early separation and later abusive mothering in monkeys: what is the pathogenic threshold?
TLDR
A nonexperimentally induced case of infant abuse by a macaque mother living in a stable social group supports the view that maternal anxiety may play a role in precipitating abuse and raises questions about etiology of primate infant abuse.
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