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Distributed and Overlapping Representations of Faces and Objects in Ventral Temporal Cortex
The functional architecture of the object vision pathway in the human brain was investigated using functional magnetic resonance imaging to measure patterns of response in ventral temporal cortex
Age-related changes in cortical blood flow activation during visual processing of faces and location
The results demonstrate that reliable age-related changes during visual processing can be found in rCBF patterns, suggesting more efficient use of occipital visual areas by younger subjects and more reliance by older subjects on one or more cortical networks, particularly for spatial vision, perhaps to compensate for reduced processing efficiency of Occipital cortex.
The functional organization of human extrastriate cortex: a PET-rCBF study of selective attention to faces and locations
The functional dissociation of human extrastriate cortical processing streams for the perception of face identity and location was investigated in healthy men by measuring visual task-related changes
The role of the anterior prefrontal cortex in human cognition
The results indicate that the fronto-polar prefrontal cortex selectively mediates the human ability to hold in mind goals while exploring and processing secondary goals, a process generally required in planning and reasoning.
Beyond sensory images: Object-based representation in the human ventral pathway.
Recognition of faces and manmade objects in sighted subjects and during tactile recognition in blind subjects showed category-related patterns of response in a ventral extrastriate visual area in the inferior temporal gyrus that were correlated across modality for man made objects.
Age-related reductions in human recognition memory due to impaired encoding.
Age-related impairments of memory may be due to a failure to encode the stimuli adequately, which is reflected in the lack of cortical and hippocampal activation during encoding.
Conjoint and extended neural networks for the computation of speech codes: the neural basis of selective impairment in reading words and pseudowords.
The results suggest that rhyming pseudowords requires active participation of extended neural systems and networks not observed for rhyming words, suggesting conjoint neural networks for phonological processing of words and Pseudoword rhyming.
Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome.
In patients presenting with cognitive symptoms of dementia, regional brain metabolism was a sensitive indicator of AD and of neurodegenerative disease in general and a negative PET scan indicated that pathologic progression of cognitive impairment during the mean 3-year follow-up was unlikely to occur.
Altered brain functional connectivity and impaired short-term memory in Alzheimer's disease.
The results support the idea of a functional disconnection between the prefrontal cortex and the hippocampus in Alzheimer's disease and suggest that memory breakdown in early Alzheimer’s disease is related to a reduction in the integrated activity within a distributed network that includes these two areas.
Sex differences in human brain morphometry and metabolism: an in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging.
Significant sex differences in aging of brain areas that are essential to higher cognitive functioning are found and may explain some of the age-sex differences in human cognition and response to brain injury and disease.