P. Peszynski

Publications29
h-index10
Citations1,736
Highly Influential Citations65
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Improvement of hepatorenal syndrome with extracorporeal albumin dialysis mars: Results of a prospective, randomized, controlled clinical trial
TLDR
It is concluded that the removal of albumin‐bound substances with the MARS method can contribute to the treatment of type I HRS.
Molecular adsorbent recycling system (MARS): clinical results of a new membrane-based blood purification system for bioartificial liver support.
TLDR
A new membrane separation system that is nearly impermeable to proteins but enables the exchange of water soluble and protein bound toxins by a special membrane and a recycled protein containing dialysate is described.
Extracorporeal detoxification using the molecular adsorbent recirculating system for critically ill patients with liver failure.
TLDR
It is concluded that the molecular adsorbent recirculating system can contribute to the treatment of critically ill patients with liver failure and different underlying diseases.
Improvement of multiple organ functions in hepatorenal syndrome during albumin dialysis with the molecular adsorbent recirculating system.
TLDR
It is concluded that MARS can improve multiple organ functions in patients with HRS and one man underwent successful liver transplantation 18 months after the treatment.
Liver support by extracorporeal blood purification: A clinical observation
TLDR
It is concluded that in acute excretory failure caused by a chronic liver disease, this treatment provides a therapy option to remove toxins involved in multiorgan dysfunction secondary to liver failure.
Albumin dialysis: single pass vs. recirculation (MARS).
TLDR
It is shown that MARS is the more effective kind of albumin dialysis for the important substances like bile acids, which are normally included in the commercial albumin solutions.
Albumin dialysis using the molecular adsorbent recirculating system
TLDR
The current knowledge about the albumin dialysis molecular adsorbent recirculating system is reviewed and the selective removal of albumin-bound end products of metabolism is reviewed.
Extracorporeal liver support by recirculating albumin dialysis: analysing the effect of the first clinically used generation of the MARSystem.
TLDR
The elimination of albumin bound and water soluble substances was accompanied by an improvement of clinical status and unwanted side-effects and changes in laboratory tests are comparable to conventional haemodialysis.
Improvement in Central Nervous System Functions During Treatment of Liver Failure with Albumin Dialysis MARS—A Review of Clinical, Biochemical, and Electrophysiological Data
TLDR
In conclusion, MARS significantly improves central nervous system functions and can serve as a model for the further investigation of the role of protein-bound substances in hepatic encephalopathy and cerebral hemodynamics.
Extracorporeal support of the failing liver
TLDR
Current knowledge suggests that extracorporeal liver support can successfully stabilize liver function, improve the clinical condition of patients, and considerably improve survival in certain subgroups of patients with fulminant hepatic failure and acute decompensation of chronic liver failure.
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