• Publications
  • Influence
Recoding a cocaine-place memory engram to a neutral engram in the hippocampus
The hippocampus provides the brain's memory system with a subset of neurons holding a map-like representation of each environment experienced. We found in mice that optogenetic silencing thoseExpand
  • 78
  • 10
  • PDF
Copines‐1, ‐2, ‐3, ‐6 and ‐7 show different calcium‐dependent intracellular membrane translocation and targeting
The copines are a family of C2‐ and von Willebrand factor A‐domain‐containing proteins that have been proposed to respond to increases in intracellular calcium by translocating to the plasmaExpand
  • 40
  • 3
  • PDF
Regulation of Dendritic Spine Morphology in Hippocampal Neurons by Copine-6
Dendritic spines compartmentalize information in the brain, and their morphological characteristics are thought to underly synaptic plasticity. Here we identify copine-6 as a novel modulator ofExpand
  • 19
  • 2
Characterization of the Intracellular Transport of GluR1 and GluR2 α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor Subunits in Hippocampal Neurons*
Little is known about the dynamics of the dendritic transport of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) to synapses. Here, using virally expressed green fluorescentExpand
  • 43
  • 1
A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space
Summary Retrieving and acting on memories of food-predicting environments are fundamental processes for animal survival. Hippocampal pyramidal cells (PYRs) of the mammalian brain provide mnemonicExpand
  • 28
  • 1
  • PDF
The second C2‐domain of copine‐2, copine‐6 and copine‐7 is responsible for their calcium‐dependent membrane association
The copine family of proteins contains nine members with a similar domain structure, namely two N‐terminal C2‐domains (C2A and C2B) and a C‐terminal A‐domain. The former are thought to be responsibleExpand
  • 8
Real-time imaging of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA receptor) movements in neurons.
The mechanisms that regulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) synthesis, transport, targeting and surface expression are of fundamental importance for fastExpand
  • 11
  • PDF