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A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer.
- J. Neoptolemos, D. Stocken, +13 authors M. Buechler
- The New England journal of medicine
- 18 March 2004
BACKGROUND The effect of adjuvant treatment on survival in pancreatic cancer is unclear. We report the final results of the European Study Group for Pancreatic Cancer 1 Trial and update the interim… Expand
Histopathological features of diagnostic and clinical relevance in autoimmune pancreatitis: a study on 53 resection specimens and 9 biopsy specimens
Background and AimsAutoimmune pancreatitis seems to be a disease with a heterogeneous appearance. Our intention was to establish key diagnostic criteria, define grades of severity and activity,… Expand
Whole-genome landscape of pancreatic neuroendocrine tumours
The diagnosis of pancreatic neuroendocrine tumours (PanNETs) is increasing owing to more sensitive detection methods, and this increase is creating challenges for clinical management. We performed… Expand
Main-Duct Intraductal Papillary Mucinous Neoplasms of the Pancreas: Clinical Predictors of Malignancy and Long-term Survival Following Resection
Objective:To describe clinical characteristics and outcomes of a large cohort of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas affecting the main pancreatic duct. Summary… Expand
Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway.
- E. Missiaglia, I. Dalai, +10 authors A. Scarpa
- Journal of clinical oncology : official journal…
- 10 January 2010
PURPOSE We investigated the global gene expression in a large panel of pancreatic endocrine tumors (PETs) aimed at identifying new potential targets for therapy and biomarkers to predict patient… Expand
Prognostic factors and survival in endocrine tumor patients: comparison between gastrointestinal and pancreatic localization.
Since gastro-entero-pancreatic endocrine tumors are rare and heterogeneous diseases, their prognosis and long-term survival are not well known. This study aimed at identifying prognostic factors and… Expand
Reconstruction by Pancreaticojejunostomy Versus Pancreaticogastrostomy Following Pancreatectomy: Results of a Comparative Study
Objective:To compare the results of pancreaticogastrostomy versus pancreaticojejunostomy following pancreaticoduodenectomy in a prospective and randomized setting. Summary Background Data:While… Expand
Pancreatic endocrine tumors: improved TNM staging and histopathological grading permit a clinically efficient prognostic stratification of patients
Pancreatic endocrine tumors are rare diseases and devising a clinically effective prognostic stratification of patients is a major clinical challenge. This study aimed at assessing whether the… Expand
A randomized multicenter clinical trial of antibiotic prophylaxis of septic complications in acute necrotizing pancreatitis with imipenem.
- P. Pederzoli, C. Bassi, S. Vesentini, A. Campedelli
- Surgery, gynecology & obstetrics
- 1 May 1993
Recent evidence of pancreatic penetration of several antibiotics active against the usual flora found in pancreatic sepsis, at therapeutic minimal inhibitory concentration, prompted the authors to… Expand
Middle Pancreatectomy: Indications, Short- and Long-term Operative Outcomes
Objective:To evaluate the indications, perioperative, and long-term outcomes of a large cohort of patients who underwent middle pancreatectomy (MP). Summary Background Data:MP is a parenchyma-sparing… Expand