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Cannabis and schizophrenia: impact on onset, course, psychopathology and outcomes
TLDR
The sample could be subdivided into two main groups, one that uses substances to counter distressing symptoms of schizophrenia and another in which cannabis might be one of the factors predisposing to the disease; the former had less negative symptoms than nonabusers. Expand
Psychopathological dimensions of depression: a factor study of the 17-item Hamilton depression rating scale in unipolar depressed outpatients.
TLDR
Though not exhibiting factorial invariance in the stricter sense of the term, the 17-item HDRS did exhibit a relatively reliable factor structure, providing further evidence that the scale is multidimensional. Expand
Alexithymia in multiple sclerosis: relationship with fatigue and depression
Objective –  The aim of this study was to investigate the prevalence of alexithymia in a sample of patients with multiple sclerosis (MS) and to further evaluate the association between alexithymiaExpand
Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methionine 1,4-butanedisulfonate (SAMe) in the treatment of major depression: comparison with imipramine in 2 multicenter studies.
TLDR
The antidepressive efficacy of S-Adenosyl-L-methionine (SAMe) orally and 400 mg SAMe/d intramuscularly is comparable with that of 150 mg imipramine/d orally, but SAMe is significantly better tolerated. Expand
The potential role of high or low birthweight as risk factor for adult schizophrenia
TLDR
The main result was that birth weight may be a risk factor for schizophrenia, as indicated by odds ratio analysis. Expand
Cardiovascular reactivity of mitral valve prolapse patients during experimental stress exposure: evidence for a functional nature of cardiovascular symptoms
TLDR
As no objective signs of cardiac rhythm modification were found in MVP patients under stress, it is postulate that the symptoms for which these patients were referred have a functional nature, and that there is no pathogenetic link with the underlying valvular defect. Expand
Double‐blind study of the efficacy and safety of sertraline versus fluoxetine in major depression
TLDR
Although there was a numerical advantage for sertraline on several efficacy measures, there was no statistically significant difference found between the treatment groups. Expand
Cannabis and Neurological Soft Signs in Schizophrenia: Absence of Relationship and Influence on Psychopathology
TLDR
Findings suggest that NSS are relatively independent from cannabis, but not from clinical features, which would suggest that non-consuming patients show a higher incidence of both NSS and negative symptoms. Expand
Atypical antipsychotics and polydipsia: a cause or a treatment?
TLDR
A brief, yet selective, overview of the current state of psychopharmacology in the treatment of PP with atypical antipsychotics in schizophrenia appears that risperidone and olanzapine are not clearly effective; clozapine may improve symptoms, although it is difficult to manage from a therapeutic point of view; quetiapine has been poorly studied so far, nonetheless it has given interesting results. Expand
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