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Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell
In situ footprinting showed that the dimerization initiation site of HIV-1 genomic RNA could be targeted by these aminoglycosides in infected cells and virions, demonstrating its accessibility. Expand
Gram-scale synthesis of uridine 5'-diphospho-N-acetylglucosamine: comparison of enzymic and chemical routes
practical chemoenzymatic and chemical routes to uridine 5'-diphospho-N'acetylglucosamine (UDP-GlcNAc) on r !ruscale have been developed. The chemoenzymatic synthesis provided convenient access toExpand
Ag-mediated reactions: coupling and heterocyclization reactions.
Versatile and expeditious synthesis of aurones via Au I-catalyzed cyclization.
Synthesis of natural 4,6,3',4'-tetramethoxyaurone and structure revision of two natural products (dalmaisione D and 4'-chloroaurone) were achieved. Expand
Synthesis, Characterization, and Catalytic Activity of Cationic NHC Gold(III) Pyridine Complexes
A series of cationic gold(I/III) pyridine complexes of the type [(L)Au(pyr)](PF6) and [(L)AuCl2(pyr)](PF6), where L = IPr, (1, 5); L = IMes (2, 6); L = ItBu, (3, 7); L = ICy (4, 8); and L = PPh3, (9,Expand
Combined small molecule and loss-of-function screen uncovers estrogen receptor alpha and CAD as host factors for HDV infection and antiviral targets
The discovery of HDV host-dependency factors elucidates the pathogenesis of viral disease biology and opens therapeutic strategies for HDV cure. Expand
Root-specific expression of opine genes and opine accumulation in some cultivars of the naturally occurring genetically modified organism Nicotiana tabacum.
It is shown that TB-mas2' is expressed at very low levels in N. tomentosiformis and in most Nicotiana tabacum cultivars; however, some cultivars show high TB-MAS2' expression levels. Expand
First evidence for the use of organosilver compounds in Pd-catalyzed coupling reactions; a mechanistic rationale for the Pd/Ag-catalyzed enyne synthesis?
This work demonstrates that organosilver compounds could enter the Pd catalytic cycle and supports the role of silver acetylides as intermediates in the new Pd/Ag-catalyzed coupling reaction. Expand
H-ZSM-5 zeolite model crystals: Structure-diffusion-activity relationship in methanol-to-olefins catalysis
Abstract Large ZSM-5 zeolite crystals synthesized in fluoride medium show an astonishing activity, stability as well as selectivity towards light olefins in the Methanol-To-Olefins (MTO) reaction. ByExpand
Chiral tridentate versus bidentate pyridines as catalysts in the enantioselective alkylation of benzaldehyde with diethylzinc
Comparison of the enantioselectivity obtained with either bidentate or tridentate chiral pyridine derivatives demonstrated that both can be very efficient catalysts for the enantioselective additionExpand