• Publications
  • Influence
Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine.
BACKGROUND Rotavirus is a leading cause of childhood gastroenteritis and death worldwide. METHODS We studied healthy infants approximately 6 to 12 weeks old who were randomly assigned to receiveExpand
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Addressing parents' concerns: do multiple vaccines overwhelm or weaken the infant's immune system?
Recent surveys found that an increasing number of parents are concerned that infants receive too many vaccines. Implicit in this concern is that the infant's immune system is inadequately developedExpand
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Rotavirus isolate WI61 representing a presumptive new human serotype.
A virus (strain WI61) representing a presumptive new human serotype was isolated from an 18-month-old child with gastroenteritis admitted to Children's Hospital of Philadelphia in February 1983. TheExpand
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Antigenic mapping of the surface proteins of rhesus rotavirus.
Monoclonal antibodies have been produced and used to map the functional topography of the surface proteins of rhesus rotavirus (RRV) that mediate viral neutralization. Ten monoclonal antibodiesExpand
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Communicating science to the public: MMR vaccine and autism.
Media attention and consequent public concerns about vaccine safety followed publication of a small case-series of children who developed autism after receipt of the measles-mumps-rubella (MMR)Expand
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The development of multivalent bovine rotavirus (strain WC3) reassortant vaccine for infants.
Laboratory and clinical studies have been directed toward development of a vaccine against rotavirus gastroenteritis in infants. First, bovine rotavirus strain WC3, which did not induce neutralizingExpand
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Vaccines and autism: a tale of shifting hypotheses.
  • J. Gerber, P. Offit
  • Medicine
  • Clinical infectious diseases : an official…
  • 15 February 2009
Although child vaccination rates remain high, some parental concern persists that vaccines might cause autism. Three specific hypotheses have been proposed: (1) the combination measles-mumps-rubellaExpand
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Development of a pentavalent rotavirus vaccine against prevalent serotypes of rotavirus gastroenteritis.
The strategy of decreasing the morbidity and mortality associated with rotavirus gastroenteritis through vaccination is supported by studies demonstrating that wild-type rotavirus infection protectsExpand
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A randomized trial to increase acceptance of childhood vaccines by vaccine-hesitant parents: a pilot study.
OBJECTIVE A cluster randomized trial was performed to evaluate an educational intervention to improve parental attitudes and vaccine uptake in vaccine-hesitant parents. METHODS Two primary careExpand
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Primary Murine Small Intestinal Epithelial Cells, Maintained in Long-Term Culture, Are Susceptible to Rotavirus Infection
ABSTRACT We describe a method for long-term culture of primary small intestinal epithelial cells (IEC) from suckling mice. IEC were digested from intestinal fragments as small intact units ofExpand
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