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Length heteroplasmy of sturgeon mitochondrial DNA: an illegitimate elongation model.
A model for the replicative origin of length differences, involving a competitive equilibrium between the heavy strand and the D-loop strand, is proposed and suggests that frequent misalignment in the repeat region prior to elongation can explain both the polymorphism and heteroplasmy in this species.
The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins
Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins
The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptor-coupled G protein
Complete cDNA encoding human phospholipid transfer protein from human endothelial cells.
A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting
The Agonist-binding Domain of the Calcium-sensing Receptor Is Located at the Amino-terminal Domain*
- H. Bräuner‐Osborne, A. A. Jensen, P. Sheppard, P. O'Hara, P. Krogsgaard‐Larsen
- BiologyThe Journal of Biological Chemistry
- 25 June 1999
A chimeric receptor named Ca/1a is constructed consisting of the ATD of CaR and the seven transmembrane region and C terminus of mGlu1a, which demonstrates that Ser-170 and to some extent Ser-147 are involved in the Ca2+ activation of the CaR, and reveals a close resemblance of the activation mechanism between the CaGlu receptors.
Cloning and analysis of the Saccharomyces cerevisiae MNN9 and MNN1 genes required for complex glycosylation of secreted proteins.
- C. Yip, S. Welch, V. Mackay
- Biology, Computer ScienceProceedings of the National Academy of Sciences…
- 29 March 1994
The MNN9 and MNN1 genes are cloned and sequenced, both of which encode proteins with the characteristics of type II membrane proteins, whereas Mnn1p is a membrane-associated protein with unknown function that is required for the addition of the long alpha 1,6-mannose backbone of the complex mannan.
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
The functional cloning of a murine complementary DNA encoding a ligand for the receptor encoded by the c-mpl proto-oncogene is reported, and results strongly suggest that theligand for c-Mpl is thrombopoietin.
Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family.
Northern analysis indicates that it occurs in at least two molecular forms and is transcribed in human brain, heart, lung, liver, and kidney, in addition to placenta, and APPH is the nearest relative of APP yet identified in an emerging multigene family.