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Length heteroplasmy of sturgeon mitochondrial DNA: an illegitimate elongation model.
TLDR
A model for the replicative origin of length differences, involving a competitive equilibrium between the heavy strand and the D-loop strand, is proposed and suggests that frequent misalignment in the repeat region prior to elongation can explain both the polymorphism and heteroplasmy in this species.
Complete cDNA encoding human phospholipid transfer protein from human endothelial cells.
The Agonist-binding Domain of the Calcium-sensing Receptor Is Located at the Amino-terminal Domain*
TLDR
A chimeric receptor named Ca/1a is constructed consisting of the ATD of CaR and the seven transmembrane region and C terminus of mGlu1a, which demonstrates that Ser-170 and to some extent Ser-147 are involved in the Ca2+ activation of the CaR, and reveals a close resemblance of the activation mechanism between the CaGlu receptors.
Cloning and analysis of the Saccharomyces cerevisiae MNN9 and MNN1 genes required for complex glycosylation of secreted proteins.
  • C. Yip, S. Welch, V. Mackay
  • Biology, Computer Science
    Proceedings of the National Academy of Sciences…
  • 29 March 1994
TLDR
The MNN9 and MNN1 genes are cloned and sequenced, both of which encode proteins with the characteristics of type II membrane proteins, whereas Mnn1p is a membrane-associated protein with unknown function that is required for the addition of the long alpha 1,6-mannose backbone of the complex mannan.
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
TLDR
The functional cloning of a murine complementary DNA encoding a ligand for the receptor encoded by the c-mpl proto-oncogene is reported, and results strongly suggest that theligand for c-Mpl is thrombopoietin.
Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family.
TLDR
Northern analysis indicates that it occurs in at least two molecular forms and is transcribed in human brain, heart, lung, liver, and kidney, in addition to placenta, and APPH is the nearest relative of APP yet identified in an emerging multigene family.
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