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Multiple forms of plasminogen activator in human breast tumors.
Total plasminogen activator (PA) activity, tissue-type PA (t-PA) activity, urokinase-like PA activity, and immunoreactive t-PA were measured in benign breast tumors (fibroadenomas), primary breastExpand
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Plasminogen activator and cancer.
  • M. Duffy, P. O'Grady
  • Chemistry, Medicine
  • European journal of cancer & clinical oncology
  • 1 May 1984
Plasminogen activator is a protease which catalyses the conversion of the inactive plasminogen to the active plasmin. Most transformed cell lines and solid tumors produce elevated levels ofExpand
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Comparison of the pharmacokinetics of fosinoprilat with enalaprilat and lisinopril in patients with congestive heart failure and chronic renal insufficiency.
AIMS To compare the serum pharmacokinetics of fosinoprilat with enalaprilat and lisinopril after 1 and 10 days of dosing with fosinopril, enalapril and lisinopril. METHODS Patients with congestiveExpand
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Pharmacokinetics of Single-Dose Oral Stavudine in Subjects with Renal Impairment and in Subjects Requiring Hemodialysis
ABSTRACT Two open-label studies assessed the pharmacokinetics of single orally administered doses of 40 mg of stavudine in subjects with renal impairment. In one study (study I), 15 subjects withExpand
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An investigation into the role of oxygen free radical scavengers in preventing polymethylmethacrylate-induced necrosis in an osteoblast cell culture.
This study examined the effect of polymethylmethacrylate (PMMA) on osteocytic necrosis and the role of free radical scavengers in minimizing this damage. Bovine osteoblast cells with a characteristicExpand
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Cytophotometric evidence for the transformation of oocytes into nurse cells inDrosophila melanogaster
SummaryA small proportion of ovarian chambers from females homozygous for theotu7 (forovariantumor) mutation contain an “oocyte” that in its nuclear morphology resembles a nurse cell. SuchExpand
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Tissue-type plasminogen activator, a new prognostic marker in breast cancer.
Plasminogen activator is a protease existing in two forms known as tissue-type and urokinase-type plasminogen activator. In this investigation, patients with breast cancers containing high levels ofExpand
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Bath administration of the quinoline antibiotic flumequine to brown trout Salmo trutta and Atlantic salmon S. salar.
Administration of flumequine to brown trout S a h o trutta and Atlantic salmon Salmo salar, using bath treatments, resulted in significant serum levels of the antibiotic. Bath concentrations of 50.Expand
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Fosinopril/hydrochlorothiazide: single dose and steady-state pharmacokinetics and pharmacodynamics.
AIMS Fosinoprilat, the active product of fosinopril, is eliminated by an hepatic pathway in addition to the renal pathway shared by other angiotensin converting enzyme inhibitors (ACEIs). This studyExpand
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