• Publications
  • Influence
Development and validation of a questionnaire to measure asthma control.
International guidelines on asthma management indicate that the primary goal of treatment should be optimum asthma control. The aim of this study was to develop and validate the Asthma ControlExpand
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An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice.
BACKGROUND The assessment of asthma control is pivotal to the evaluation of treatment response in individuals and in clinical trials. Previously, asthma control, severity, and exacerbations wereExpand
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A summary of the new GINA strategy: a roadmap to asthma control
Over the past 20 years, the Global Initiative for Asthma (GINA) has regularly published and annually updated a global strategy for asthma management and prevention that has formed the basis for manyExpand
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Treatment of asthma with drugs modifying the leukotriene pathway.
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Low dose inhaled budesonide and formoterol in mild persistent asthma: the OPTIMA randomized trial.
The optimal treatment for mild asthma is uncertain. We assessed the effects of adding a long-acting inhaled beta-agonist, formoterol, to low doses of an inhaled corticosteroid, budesonide, for 1 yrExpand
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Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma.
Asthma is a global health problem affecting around 300 million individuals of all ages, ethnic groups and countries. It is estimated that around 250,000 people die prematurely each year as a resultExpand
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Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults
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Mepolizumab for prednisone-dependent asthma with sputum eosinophilia.
BACKGROUND Eosinophilic inflammation, which may be a consequence of interleukin-5 action, is a characteristic feature of some forms of asthma. However, in three previous clinical trials involvingExpand
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Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis.
RATIONALE The clinical management of idiopathic pulmonary fibrosis (IPF) remains a major challenge due to lack of effective drug therapy or accurate indicators for disease progression. Fibrocytes areExpand
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