Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter
- A. Salahpour, A. Ramsey, M. Caron
- Biology, PsychologyProceedings of the National Academy of Sciences
- 18 March 2008
The results suggest that overexpression of DAT leads to a marked increase in sensitivity to psychomotor and rewarding properties of amphetamine.
Alternate signalling pathways from the interleukin-2 receptor.
- J. Ellery, P. Nicholls
- BiologyCytokine & growth factor reviews
- 1 February 2002
Neuroanatomical phenotypes in the Reeler mouse
- A. Badea, P. Nicholls, G. Johnson, W. Wetsel
- Biology, PsychologyNeuroImage
- 15 February 2007
Expression and characterization of recombinant human eosinophil-derived neurotoxin and eosinophil-derived neurotoxin-anti-transferrin receptor sFv.
- D. Newton, P. Nicholls, S. Rybak, R. Youle
- BiologyJournal of Biological Chemistry
- 28 October 1994
The structure of the llama heavy chain constant genes reveals a mechanism for heavy-chain antibody formation
- B. P. Woolven, L. Frenken, P. van der Logt, P. Nicholls
- Biology, MedicineImmunogenetics
- 1 October 1999
Internalization of a Bacillus anthracis Protective Antigen-c-Myc Fusion Protein Mediated by Cell Surface Anti-c-Myc Antibodies
- M. Varughese, A. Chi, A. Teixeira, P. Nicholls, J. Keith, S. Leppla
- Biology, ChemistryMolecular Medicine
- 1 February 1998
This study shows that PA can be redirected to alternate receptors by adding novel epitopes to the C-terminus of PA, enabling the creation of cell-directed toxins for therapeutic purposes.
Expression of an anti-CD33 single-chain antibody by Pichia pastoris.
- L. Emberson, A. J. Trivett, P. Blower, P. Nicholls
- BiologyJIM - Journal of Immunological Methods
- 30 October 2005
The role of proline 345 in diphtheria toxin translocation.
- V. G. Johnson, P. Nicholls, W. Habig, R. Youle
- Biology, ChemistryJournal of Biological Chemistry
- 15 February 1993
A functional alternative splicing mutation in human tryptophan hydroxylase-2
- X. Zhang, P. Nicholls, M. Caron
- BiologyMolecular Psychiatry
- 21 September 2010
A common, but functional single-nucleotide polymorphism (SNP rs1386493) in the TPH2 gene is characterized, which decreases efficiency of normal RNA splicing, resulting in a truncated T PH2 protein (TPH2-TR) by alternative splicing.
Integrated approaches to understanding antipsychotic drug action at GPCRs.
- N. Urs, P. Nicholls, M. Caron
- Biology, MedicineCurrent Opinion in Cell Biology
- 1 April 2014
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