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p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2.
TLDR
Evidence is presented that the approximately 100-kDa ansamycin-binding protein is GRP94, which disrupts this complex, leading to degradation of pre-existing p185erbB2 protein, and resulting in an altered subcellular distribution of newly synthesized p185lbB2. Expand
The Enamel Protein Amelogenin Binds to the N-Acetyl-d-glucosamine-mimicking Peptide Motif of Cytokeratins*
TLDR
It is documents that molecular mimicry may play a role in stability and organization of amelogenin during amelogenesis. Expand
p185 Binds to GRP94 in Vivo
TLDR
Evidence is presented that GA binding to GRP94 disrupts this complex, leading to degradation of pre-existing p185 protein, and resulting in an altered subcellular distribution of newly synthesized p185. Expand