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Heterogeneities in the transmission of infectious agents: implications for the design of control programs.
From an analysis of the distributions of measures of transmission rates among hosts, we identify an empirical relationship suggesting that, typically, 20% of the host population contributes at leastExpand
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Association between genital schistosomiasis and HIV in rural Zimbabwean women
Objective:To determine the association between female genital Schistosoma haematobium infection and HIV. Design and methods:A cross-sectional study with a 1-year follow-up. Gynecological andExpand
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Simple clinical manifestations of genital Schistosoma haematobium infection in rural Zimbabwean women.
Up to 75% of women with urinary schistosomiasis have Schistosoma haematobium ova in the genitals. This study aimed to describe the prevalence of gynecologic S. haematobium infection and toExpand
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A review of female genital schistosomiasis.
In a review of the studies on genital schistosomiasis, the cervix, the Fallopian tubes, and the vagina are the most common gynaecological sites to harbour Schistosoma haematobium. Lesions are causedExpand
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Effect of multimicronutrient supplementation on gestational length and birth size: a randomized, placebo-controlled, double-blind effectiveness trial in Zimbabwe.
BACKGROUND Multiple micronutrient deficiencies may contribute to low birth weight, which is a major global determinant of mortality. OBJECTIVE We assessed the effect of prenatal multimicronutrientExpand
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A comparison of humoral responses to Schistosoma haematobium in areas with low and high levels of infection
Antibody responses to Schistosoma haematobium of 280 Zimbabweans were studied in two areas of differing infection levels. 133 of the subjects came from a low infection area with a prevalence of 33.8%Expand
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Human papillomavirus in a rural community in Zimbabwe: The impact of HIV co‐infection on HPV genotype distribution
Cervical cancer is a leading cause of cancer‐related deaths in developing countries, and the human papillomavirus (HPV) is linked etiologically to cervical cancer. Hence, a vaccine which preventsExpand
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Chemotherapy accelerates the development of acquired immune responses to Schistosoma haematobium infection.
Treatment of 41 Schistosoma haematobium-infected children, 5-16 years old, with the drug praziquantel induced a switch from a predominantly IgA-specific antibody response to a predominantly IgG1Expand
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Heterogeneities in schistosome transmission dynamics and control.
We review the theoretical framework for exploring the impact of individual and spatial heterogeneities in patterns of exposure and contamination and on the basic reproduction number, R0, for humanExpand
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Age‐related antibody profiles in Schistosoma haematobium infections in a rural community in Zimbabwe
Antibody responses to soluble Schistosoma haematobium egg (SEA) and worm (SWA) antigens in a rural Zimbabwean study population were examined by ELISA. One hundred and sixteen S. haematobium infectedExpand
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