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Glatiramer acetate in primary progressive multiple sclerosis: Results of a multinational, multicenter, double‐blind, placebo‐controlled trial
TLDR
To determine whether glatiramer acetate slows accumulation of disability in primary progressive multiple sclerosis, a new drug is developed that acts as a ‘spatially aggregating agent’ to reduce the risk of disease progression.
Demonstration of interstitial cerebral edema with diffusion tensor MR imaging in type C hepatic encephalopathy
TLDR
The increase in MD with no concomitant changes in FA in cirrhosis with minimal or early HE indicates the presence of reversible interstitial brain edema.
In vivo serial diffusion tensor imaging of experimental spinal cord injury
TLDR
In vivo longitudinal diffusion tensor imaging of rodent spinal cord injury was carried out over a period of eight weeks post‐injury and overall the DTI metrics were observed to be closer to the normal tissue values in the caudal relative to the rostral sections (rostral–caudal asymmetry).
Reduced Anterior Corpus Callosum White Matter Integrity is Related to Increased Impulsivity and Reduced Discriminability in Cocaine-Dependent Subjects: Diffusion Tensor Imaging
TLDR
The finding that reduced integrity of anterior corpus callosum white matter in cocaine users is related to impaired impulse control and reduced ability to discriminate between target and catch stimuli is consistent with prior theories regarding frontal cortical involvement in impaired inhibitory control in cocaine-dependent subjects.
Phase-sensitive T1 inversion recovery imaging: a time-efficient interleaved technique for improved tissue contrast in neuroimaging.
TLDR
PS-T1IR has the highest contrast-to-noise ratio (CNR) efficiency compared with T1FLAIR and T1SE and is a very practical technique for neuroradiologic applications.
Serial changes in the white matter diffusion tensor imaging metrics in moderate traumatic brain injury and correlation with neuro-cognitive function.
TLDR
DTI demonstrates axonopathy in the acute stage, as well as at secondary stages, at 6 months post-injury in the corpus callosum and peri-ventricular white matter in regions of normal-appearing white matter on conventional MRI.
Diffusion tensor fractional anisotropy of the normal‐appearing seven segments of the corpus callosum in healthy adults and relapsing‐remitting multiple sclerosis patients
To investigate the utility of whole‐brain diffusion tensor imaging (DTI) in elucidating the pathogenesis of multiple sclerosis (MS) using the normal‐appearing white matter (NAWM) of the corpus
Proton magnetic resonance spectroscopy in multiple sclerosis.
Diffusion tensor imaging of the developing human cerebrum
TLDR
The studies suggest that the DTI‐estimated anisotropy could be useful in following neuronal migration, cortical maturation, and associated changes in the germinal matrix during early brain development.
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