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Tryptophan Metabolism via the Kynurenine Pathway in Experimental Chronic Renal Failure
Background: Kidneys are involved in tryptophan (TRP) metabolism in two ways. They eliminate TRP derivatives on the one hand, and they produce several enzymes taking part in TRP metabolism mainly viaExpand
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The diagnostics of colorectal cancer
Colorectal cancer (CRC) is one of the most frequent human malignant neoplasms. CRC has an estimated incidence of more than 1,000,000 new cases annually worldwide. Approximately one out of threeExpand
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Serum levels of granulocyte colony-stimulating factor (G-CSF) and macrophage colony-stimulating factor (M-CSF) in pancreatic cancer patients
Abstract Background: Pancreatic cancer is an aggressive malignancy of the gastrointestinal tract and one of the most lethal human cancers. It has been shown that endogenous cytokines, producedExpand
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Serum fatty acid profile in psoriasis and its comorbidity
Psoriasis is a chronic inflammatory skin disease that is accompanied by metabolic disturbances and cardio-metabolic disorders. Fatty acids (FAs) might be a link between psoriasis and its comorbidity.Expand
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[Diagnostic difficulties in adrenal incidentaloma--analysis of 125 cases].
INTRODUCTION Therapeutic approach to incidentaloma, in spite of existing algorithms, is not always obvious due to diagnostic difficulties. The aim of the study was to assess the validity of theExpand
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Increase in circulating sphingosine-1-phosphate and decrease in ceramide levels in psoriatic patients
Psoriasis is characterized by hyperproliferation, deregulated differentiation and impaired apoptosis of keratinocytes. Mechanisms of lipid profile disturbances and metabolic syndrome in the psoriaticExpand
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[The clinical significance of fatty acid binding proteins].
Excessive levels of free fatty acids are toxic to cells. The human body has evolved a defense mechanism in the form of small cytoplasmic proteins called fatty acid binding proteins (FABPs) that bindExpand
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Soluble angiogenesis markers in gastric tumor patients.
Gastric cancer is the second commonest cause of cancer-associated death in the world. Its molecular markers can be useful not only for diagnostic, but also prognostic purposes. The aim of the studyExpand
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IGF-IR in patients with advanced colorectal cancer in correlation with certain clinico-morphological factors: Initial report.
The insulin-like growth factor (IGF) system comprises two types of peptides (IGF-I and IGF-II), two types of receptors (IGF-IR and IGF-IIR) and six IGF-binding proteins (BP). This system is mainlyExpand
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Videoscopic adrenalectomy – when does retroperitoneal seem better?
Introduction Videoscopic adrenalectomy is the gold standard for the surgical treatment of benign adrenal tumours. The two most common approaches are the lateral transperitoneal approach (LTA) and theExpand
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