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Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers.
TLDR
It is shown that free radical production is increased in patients with COPD and that smoking causes an acute increase in oxidative stress, as reflected by 8-isoprostane concentrations in breath condensate. Expand
Acute Effects of Air Pollution on Pulmonary Function, Airway Inflammation, and Oxidative Stress in Asthmatic Children
TLDR
Air pollution may increase airway oxidative Stress and decrease small airway function of asthmatic children and inhaled corticosteroids may reduce oxidative stress and improveAirway function. Expand
Isoprostanes: markers and mediators of oxidative stress
TLDR
Measurement of F2‐isoprostanes has emerged as one of the most reliable approaches to assess oxidative stress status in vivo, providing an important tool to explore the role of oxidative stress in the pathogenesis of human disease. Expand
Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients.
TLDR
It is shown that oxidative stress is increased in asthmatic subjects as reflected by 8-isoprostane concentrations in breath condensate, which is a biomarker of oxidative stress in the airways. Expand
Exhaled leukotrienes and prostaglandins in COPD
TLDR
There is a selective increase in exhaled LTB4 and PGE2 in patients with COPD which may be relatively resistant to inhaled corticosteroid therapy. Expand
Increased nitrosothiols in exhaled breath condensate in inflammatory airway diseases.
TLDR
It is shown that RS-NOs are detectable in exhaled breath condensate of healthy subjects and are increased in patients with inflammatory airway diseases and in current smokers. Expand
Diagnosing Nonimmediate Reactions to Penicillins by in vivo Tests
TLDR
Both patch and intradermal tests are useful in evaluating nonimmediate reactions to penicillins, particularly maculopapular rashes, and patch test and delayed intrader mal positivity together indicate delayed hypersensitivity. Expand
Gas chromatography/mass spectrometry analysis of exhaled leukotrienes in asthmatic patients
TLDR
Gas chromatography/mass spectrometry can be used to accurately quantify exhaled LTs which are increased in asthmatic adults and children compared with controls. Expand
A European Respiratory Society technical standard: exhaled biomarkers in lung disease
TLDR
Application of breath biomarker measurement in a standardised manner will provide comparable results, thereby facilitating the potential use of these biomarkers in clinical practice, and highlighting future research priorities in the field. Expand
Exhaled carbon monoxide and nitric oxide in COPD.
TLDR
The measurement of exhaled CO and NO may represent a new method for the noninvasive monitoring of airway inflammation and oxidant stress in COPD ex-smokers. Expand
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