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- Publications
- Influence
Influence of ionic inorganic solutes on self-assembly and polymerization processes related to early forms of life: implications for a prebiotic aqueous medium.
- P. Monnard, C. L. Apel, A. Kanavarioti, D. Deamer
- Chemistry, Medicine
- Astrobiology
- 2002
A commonly accepted view is that life began in a marine environment, which would imply the presence of inorganic ions such as Na+, Cl-, Mg2+, Ca2+, and Fe2+. We have investigated two processes… Expand
Prebiotically relevant mixed fatty acid vesicles support anionic solute encapsulation and photochemically catalyzed trans-membrane charge transport
- Jonathan L Cape, P. Monnard, J. Boncella
- Chemistry
- 14 March 2011
The spontaneous assembly of amphiphile-based compartments in aqueous solution is widely viewed as a key step in models for the abiotic formation of primitive cell-like structures. Proposed organic… Expand
Preparation of vesicles from nonphospholipid amphiphiles.
- P. Monnard, D. Deamer
- Medicine, Chemistry
- Methods in enzymology
- 2003
Publisher Summary This chapter describes the properties and preparation of lipid vesicles from the simplest kinds of amphiphilic compounds. It addresses issues of stability, permeability, and… Expand
OPARIN'S REACTIONS REVISITED : ENZYMATIC SYNTHESIS OF POLY(ADENYLIC ACID) IN MICELLES AND SELF-REPRODUCING VESICLES
- P. Walde, A. Goto, P. Monnard, Michaela Wessicken, P. Luisi
- Chemistry
- 1 August 1994
Membrane self‐assembly processes: Steps toward the first cellular life
- P. Monnard, D. Deamer
- Biology, Medicine
- The Anatomical record
- 1 November 2002
This review addresses the question of the origin of life, with emphasis on plausible boundary structures that may have initially provided cellular compartmentation. Some form of compartmentation is a… Expand
Eutectic phase polymerization of activated ribonucleotide mixtures yields quasi-equimolar incorporation of purine and pyrimidine nucleobases.
- P. Monnard, A. Kanavarioti, D. Deamer
- Chemistry, Medicine
- Journal of the American Chemical Society
- 21 October 2003
The RNA world hypothesis requires a plausible mechanism by which RNA itself (or precursor RNA-like polymers) can be synthesized nonenzymatically from the corresponding building blocks. Simulation… Expand
Current Ideas about Prebiological Compartmentalization
- P. Monnard, P. Walde
- Biology, Medicine
- Life
- 10 April 2015
Contemporary biological cells are highly sophisticated dynamic compartment systems which separate an internal volume from the external medium through a boundary, which controls, in complex ways, the… Expand
Nucleobase mediated, photocatalytic vesicle formation from an ester precursor.
- Michael S. DeClue, P. Monnard, +5 authors J. Boncella
- Chemistry, Medicine
- Journal of the American Chemical Society
- 28 January 2009
We report the use of photoinduced electron transfer to drive reductive cleavage of an ester to produce bilayer-forming molecules; specifically, visible photolysis in a mixture of a decanoic acid… Expand
Nutrient Uptake by Protocells: A Liposome Model System
- P. Monnard, D. Deamer
- Biology, Medicine
- Origins of life and evolution of the biosphere
- 1 February 2001
Over the past decade, several liposome-basedmodels for protocells have been developed. Forexample, liposome systems composed of polymeraseenzymes encapsulated with their substrates havedemonstrated… Expand
Models of primitive cellular life: polymerases and templates in liposomes
- P. Monnard, A. Lupták, D. Deamer
- Biology, Medicine
- Philosophical Transactions of the Royal Society B…
- 29 October 2007
Nutrient transport, polymerization and expression of genetic information in cellular compartments are hallmarks of all life today, and must have appeared at some point during the origin and early… Expand