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Influence of ionic inorganic solutes on self-assembly and polymerization processes related to early forms of life: implications for a prebiotic aqueous medium.
A commonly accepted view is that life began in a marine environment, which would imply the presence of inorganic ions such as Na+, Cl-, Mg2+, Ca2+, and Fe2+. We have investigated two processesExpand
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Prebiotically relevant mixed fatty acid vesicles support anionic solute encapsulation and photochemically catalyzed trans-membrane charge transport
The spontaneous assembly of amphiphile-based compartments in aqueous solution is widely viewed as a key step in models for the abiotic formation of primitive cell-like structures. Proposed organicExpand
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Preparation of vesicles from nonphospholipid amphiphiles.
Publisher Summary This chapter describes the properties and preparation of lipid vesicles from the simplest kinds of amphiphilic compounds. It addresses issues of stability, permeability, andExpand
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Membrane self‐assembly processes: Steps toward the first cellular life
This review addresses the question of the origin of life, with emphasis on plausible boundary structures that may have initially provided cellular compartmentation. Some form of compartmentation is aExpand
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Eutectic phase polymerization of activated ribonucleotide mixtures yields quasi-equimolar incorporation of purine and pyrimidine nucleobases.
The RNA world hypothesis requires a plausible mechanism by which RNA itself (or precursor RNA-like polymers) can be synthesized nonenzymatically from the corresponding building blocks. SimulationExpand
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Current Ideas about Prebiological Compartmentalization
Contemporary biological cells are highly sophisticated dynamic compartment systems which separate an internal volume from the external medium through a boundary, which controls, in complex ways, theExpand
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Nucleobase mediated, photocatalytic vesicle formation from an ester precursor.
We report the use of photoinduced electron transfer to drive reductive cleavage of an ester to produce bilayer-forming molecules; specifically, visible photolysis in a mixture of a decanoic acidExpand
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Nutrient Uptake by Protocells: A Liposome Model System
  • P. Monnard, D. Deamer
  • Biology, Medicine
  • Origins of life and evolution of the biosphere
  • 1 February 2001
Over the past decade, several liposome-basedmodels for protocells have been developed. Forexample, liposome systems composed of polymeraseenzymes encapsulated with their substrates havedemonstratedExpand
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Models of primitive cellular life: polymerases and templates in liposomes
Nutrient transport, polymerization and expression of genetic information in cellular compartments are hallmarks of all life today, and must have appeared at some point during the origin and earlyExpand
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