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Pancreastatin inhibits insulin secretion as induced by glucagon, vasoactive intestinal peptide, gastric inhibitory peptide, and 8-cholecystokinin in the perfused rat pancreas.
Inhibitory effect of rat amylin on the insulin responses to glucose and arginine in the perfused rat pancreas
Somatostatin, insulin and glucagon secretion by the perfused pancreas from the cysteamine-treated rat.
Effects of pancreastatin on insulin, glucagon and somatostatin secretion by the perfused rat pancreas.
Effects of galanin on hormone secretion from the in situ perfused rat pancreas and on glucose production in rat hepatocytes in vitro.
- R. Silvestre, P. Miralles, L. Monge, P. Moreno, M. L. Villanueva, J. Marco
- Biology, MedicineEndocrinology
- 1 July 1987
Galanin inhibited insulin secretion without modifying glucagon and somatostatin output, thus pointing to a direct effect of galanin on the B cell; and in rat hepatocytes, Galanin did not affect glycogenolysis or gluconeogenesis; hence, the reported hyperglycemia induced by exogenous galan in does not seem to be accounted for by a directEffect of this peptide on hepatic glucose production.
Inhibitory effect of galanin on pancreatic polypeptide release by the perfused rat pancreas.
Effects of galanin on islet cell secretory responses to VIP, GIP, 8-CCK, and glucagon by the perfused rat pancreas.
Inhibition of Insulin and Somatostatin Secretion and Stimulation of Glucagon Release by Homologous Galanin in Perfused Rat Pancreas
The opposite effects of galanin on insulin and glucagon secretion favor the concept of Galanin as a diabetogenic agent.
Homologous pancreastatin inhibits insulin secretion without affecting glucagon and somatostatin release in the perfused rat pancreas