• Publications
  • Influence
Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG)
TLDR
With increasing numbers of complete RV genome sequences becoming available, a standardized RV strain nomenclature system is needed, and the RCWG proposes that individual RV strains are named as follows: RV group/species of origin/country of identification/common name/year of identification /G- and P-type. Expand
Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments
TLDR
A Rotavirus Classification Working Group (RCWG) including specialists in molecular virology, infectious diseases, epidemiology, and public health was formed, which can assist in the appropriate delineation of new genotypes, thus avoiding duplications and helping minimize errors. Expand
The dsRNA viruses.
  • P. Mertens
  • Biology, Medicine
  • Virus research
  • 1 April 2004
TLDR
To facilitate the identification and comparisons of cognate proteins from different species, genera and families of dsRNA viruses, a series of tables were originally constructed and have now been updated and extended and are available from the ds RNA virus website at. Expand
Rapid cDNA synthesis and sequencing techniques for the genetic study of bluetongue and other dsRNA viruses.
TLDR
Improved methods for sequence-independent synthesis of full-length cDNA copies of dsRNA genes and associated sequencing strategies are described and make it possible to generate sequence data rapidly from multiple isolates for molecular epidemiology studies. Expand
Detection of a Fourth Orbivirus Non-Structural Protein
TLDR
Bioinformatic analyses indicate that NS4 contains coiled-coils, is related to proteins that bind nucleic acids, or are associated with membranes and shows similarities to nucleolar protein UTP20 (a processome subunit). Expand
The bluetongue virus core: a nano-scale transcription machine.
TLDR
The structure of the BTV core particle has been determined to atomic resolution by X-ray crystallography, revealing the organisation and interactions of its major protein components and important features of the packaged dsRNA. Expand
The barriers to bluetongue virus infection, dissemination and transmission in the vector, Culicoides variipennis (Diptera: Ceratopogonidae)
TLDR
The most important barriers to BTV transmission in Culicoides vector species appeared to be a mesenteron infection barrier, which controls initial establishment of persistent infection, a mesEnteron escape barrier (MEB) which can restrict virus to gut cells and a dissemination barrier (DB), which can prevent virus which enters the haemocoel from infecting secondary target organs. Expand
Full Genome Characterisation of Bluetongue Virus Serotype 6 from the Netherlands 2008 and Comparison to Other Field and Vaccine Strains
TLDR
Two genome segments of the virus showed significant differences from the BTV-6 vaccine, indicating that they had been acquired by reassortment event with B TV-8, and another unknown parental-strain, which suggests that the virus was in the process of reassorting with the northern field strain of Btv-8. Expand
Novel Bluetongue Virus Serotype from Kuwait
TLDR
Nucleotide sequencing identified KUW2010/02 as a novel BTV serotype, and caused mild clinical signs in sheep. Expand
Transmission Pathways of Foot-and-Mouth Disease Virus in the United Kingdom in 2007
TLDR
Complete genome sequence analysis of FMD viruses conducted in real-time has identified the initial and intermediate sources of these outbreaks and demonstrate the value of such techniques in providing information useful to contemporary disease control programmes. Expand
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