• Publications
  • Influence
Characterization of benzo[a]pyrene metabolites formed by 3-methylcholanthrene-induced goldfish, black bullhead and brown bullhead.
  • L. Swain, P. Melius
  • Chemistry, Medicine
  • Comparative biochemistry and physiology. C…
  • 1984
Metabolites of BaP formed by 3-MC-induced goldfish (Carassius auratus), black bullhead (Ictalurus melas), brown bullhead (Ictalurus nebulus) and rat have been separated by HPLC. The main metabolitesExpand
  • 22
  • 1
Experimental retracement of the origins of a protocell
Although Oparin used coacervate droplets from two or more types of polymer to model the first cell, he hypothesized homacervation from protein, consistent with Pasteur and Darwin. Herrera made twoExpand
  • 18
  • 1
Isolation of yeast invertase by sephadex gel chromatography. A biochemistry laboratory experiment.
  • P. Melius
  • Chemistry, Medicine
  • Journal of chemical education
  • 1 November 1971
The author shares this experiment, which was developed because he needed to illustrate protein and enzyme isolation and purification, which was suitable for an undergraduate laboratory.
  • 13
  • 1
Differential centrifugation of bovine parathyroid tissue.
  • 14
Barbital stabilization of a purified leucine aminopeptidase against EDTA inactivation.
  • 7
Polynuclear aromatic hydrocarbon metabolism in fishes.
  • B. Tan, P. Melius
  • Chemistry, Medicine
  • Comparative biochemistry and physiology. C…
  • 1986
  • 27
Comparative benzo[a]pyrene metabolite patterns in fish and rodents.
  • P. Melius
  • Chemistry, Medicine
  • National Cancer Institute monograph
  • 1 May 1984
Benzo[a]pyrene is converted to 3-hydroxybenzo[a]pyrene, 9-hydroxybenzo[a]pyrene, benzo[a]pyrene-4,5-dihydrodiol, benzo[a]pyrene-7,8-dihydrodiol, benzo[a]pyrene-9,10-dihydrodiol, and benzo[a]pyreneExpand
  • 13
Inhibition of leucine aminopeptidase and malate dehydrogenase by aquoplatinum (II) complexes.
Abstract Halide complexes of platinum have been previously shown to inhibit tumors and cell growth as well as to possess immunosuppresive activity. Evidence is presented here that the active speciesExpand
  • 12
Papillomas on fish exposed to chlorinated wastewater effluent.
The presence of carcinogenic and mutagenic chemical(s) in the effluent of a wastewater treatment plant was indicated by papillomas developing on caged black bullheads (Ictalurus melas), hepaticExpand
  • 53
Inhibition of leucine aminopeptidase by halide complexes of platinum.
  • 12