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Birth defects after maternal exposure to corticosteroids: prospective cohort study and meta-analysis of epidemiological studies.
TLDR
Although prednisone does not represent a major teratogenic risk in humans at therapeutic doses, it does increase by an order of 3.4-fold the risk of oral cleft, which is consistent with the existing animal studies.
GABAergic Function in Alzheimer's Disease: Evidence for Dysfunction and Potential as a Therapeutic Target for the Treatment of Behavioural and Psychological Symptoms of Dementia
TLDR
Evidence for disruptions in GABA among patients with AD is reviewed and it is suggested that the variable findings reflect subtypes of the disease that are possibly manifested clinically by differing behavioural symptoms.
Role of serotonin in the behavioral and psychological symptoms of dementia.
TLDR
Serotonergic therapies may be used to manipulate other neurotransmitters systems to alleviate BPSD or in combination with agents specific for the other neurotransmitter receptor sites.
Oncologists' strategies and barriers to effective communication about the end of life.
TLDR
It is suggested that further research and intervention are necessary to aid oncologists in achieving effective communication about end-of-life issues.
Fetal Safety of Drugs Used in the Treatment of Allergic Rhinitis
TLDR
There are many safe treatment options for the clinician when dealing with allergic rhinitis during pregnancy, and recommendations should be based both on the safety of the drugs during pregnancy and the comparative efficacy of the agent in the treatment of the underlying condition.
Evidence-based view of safety and effectiveness of pharmacologic therapy for nausea and vomiting of pregnancy (NVP).
TLDR
Many medications, particularly H(1)-antagonists and phenothiazines, are safe and effective for treatment of varying degrees of NVP.
Psychosocial morbidity among women with nausea and vomiting of pregnancy: Prevalence and association with anti-emetic therapy
TLDR
It is concluded that psychosocial morbidity is evident across the spectrum of severity of nausea and vomiting among women with NVP, as reflected by women's decisions to take anti-emetics as a reflection of their distress due to NVP.
Nature and impact of grief over patient loss on oncologists' personal and professional lives.
TLDR
Poverty, food insecurity, and obesity: a conceptual framework for research, practice, and policy, and the role of energy density and energy costs.
A Risk-Benefit Assessment of Pharmacological and Nonpharmacological Treatments for Nausea and Vomiting of Pregnancy
TLDR
A risk-benefit analysis of the literature on safety and effectiveness of pharmacotherapy and nontraditional therapy for nausea and vomiting of pregnancy (NVP) is summarised to provide evidence-based guidelines on the management of NVP.
Choice of Breastfeeding and Physicians' Advice: A Cohort Study of Women Receiving Propylthiouracil
TLDR
A substantial proportion of the lactating patients on PTU still receive advice against breastfeeding from their physicians, and Physicians' advice and attitudes toward breastfeeding during PTU therapy are a major factor in women's final decision to breastfeed.
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