• Publications
  • Influence
The Role of TLR2 in Infection and Immunity
Toll-like receptors (TLRs) are recognition molecules for multiple pathogens, including bacteria, viruses, fungi, and parasites. TLR2 forms heterodimers with TLR1 and TLR6, which is the initial stepExpand
  • 267
  • 22
Cutting Edge: Immune Stimulation by Neisserial Porins Is Toll-Like Receptor 2 and MyD88 Dependent1
The immunopotentiating activity of neisserial porins, the major outer membrane protein of the pathogenic Neisseria, is mediated by its ability to stimulate B cells and up-regulate the surfaceExpand
  • 315
  • 16
Customer satisfaction and loyalty in a digital environment: an empirical test
Purpose – The purpose of this paper is to explore the links between customer loyalty attitude, customer loyalty behaviours (measured by customer purchase behaviours) and profitability. The aim is toExpand
  • 167
  • 11
TLR-Dependent Human Mucosal Epithelial Cell Responses to Microbial Pathogens
Toll-like receptor (TLR) signaling represents one of the best studied pathways to implement defense mechanisms against invading microbes in human being as well as in animals. TLRs respond to specificExpand
  • 143
  • 10
Meningococcal Porin PorB Binds to TLR2 and Requires TLR1 for Signaling1
TLR2 plays a key role in the initiation of the cellular innate immune responses by a wide range of bacterial products. TLRs signaling, including TLR2 and its coreceptors TLR1 and TLR6, is mediated byExpand
  • 144
  • 7
The role of porins in neisserial pathogenesis and immunity.
Neisseria meningitidis and Neisseria gonorrhoeae are Gram-negative pathogenic bacteria responsible for bacterial meningitis and septicemia, and the sexually transmitted disease gonorrhea,Expand
  • 161
  • 5
Macrophage-Specific TLR2 Signaling Mediates Pathogen-Induced TNF-Dependent Inflammatory Oral Bone Loss
Porphyromonas gingivalis is a primary etiological agent of chronic periodontal disease, an infection-driven chronic inflammatory disease that leads to the resorption of tooth-supporting alveolarExpand
  • 92
  • 5
Neisserial Porin-Induced Dendritic Cell Activation Is MyD88 and TLR2 Dependent1
Neisserial porins have been shown to act as B cell mitogens and immune adjuvants. PorA and PorB are the major outer membrane porin proteins of the human pathogen Neisseria meningitidis. We have shownExpand
  • 92
  • 4
Toll-Like Receptor 2-Dependent Activity of Native Major Outer Membrane Protein Proteosomes of Chlamydia trachomatis
ABSTRACT Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen and the etiologic agent of blinding trachoma. Intracellular signaling pathways leading to host cellExpand
  • 25
  • 3
Toll-like receptor 2 induces mucosal homing receptor expression and IgA production by human B cells.
There is a need for developing vaccines that elicit mucosal immunity. Although oral or nasal vaccination methods would be ideal, current strategies have yielded mixed success. Toll-like receptor 2Expand
  • 28
  • 3