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Comparative teratogenicity of chlorpyrifos and malathion on Xenopus laevis development.
The embryotoxic potential of chlorpyrifos (CPF) and malathion (MTN), two organophosphorus insecticides (OPs), was evaluated by modified Frog Embryo Teratogenesis Assay-Xenopus (FETAX). CPF and MTNExpand
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Winter fine particulate matter from Milan induces morphological and functional alterations in human pulmonary epithelial cells (A549).
Samples of PM(2.5) were gravimetrically collected during the winter 2005/2006 in the urban area of Milan (North Italy). Samples were chemically characterized and the particles were detached fromExpand
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Nano-sized CuO, TiO2 and ZnO affect Xenopus laevis development
Abstract The teratogenic potential of commercially available copper oxide (CuO), titanium dioxide (TiO2) and zinc oxide (ZnO) nanoparticles (NPs) was evaluated using the standardized FETAX test.Expand
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Impact of tire debris on in vitro and in vivo systems
BackgroundIt is estimated that over 80% of respirable particulate matter (PM10) in cities comes from road transport and that tire and brake wear are responsible for the 3–7% emission of it. Data onExpand
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The modality of cell-particle interactions drives the toxicity of nanosized CuO and TiO₂ in human alveolar epithelial cells.
Metal oxide NPs are abundantly produced in nanotech industries and are emitted in several combustion processes, suggesting the need to characterize their toxic impact on the human respiratory system.Expand
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Lung toxicity induced by intratracheal instillation of size-fractionated tire particles.
Tire particles (TP) represent a significant component of urban air pollution (PM), constituting more than 10% of PM10 mass at urban locations with heavy traffic. The purpose of this study was toExpand
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Gene expression profiling of A549 cells exposed to Milan PM2.5.
BACKGROUND Particulate matter (PM) has been associated to adverse health effects in exposed population and DNA damage has been extensively reported in in vitro systems exposed to fine PM (PM2.5). TheExpand
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PM10‐biogenic fraction drives the seasonal variation of proinflammatory response in A549 cells
PM10 was collected in a Milan urban site, representative of the city air quality, during winter and summer 2006. Mean daily PM10 concentration was 48 μg m−3 during summer and 148 μg m−3 duringExpand
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Season linked responses to fine and quasi-ultrafine Milan PM in cultured cells.
Exposure to urbane airborne particulate matter (PM) is related to the onset and exacerbation of cardiovascular and respiratory diseases. The fine (PM1), and quasi-ultrafine (PM0.4) Milan particlesExpand
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Evidence and uptake routes for Zinc oxide nanoparticles through the gastrointestinal barrier in Xenopus laevis
Abstract The developmental toxicity of nanostructured materials, as well as their impact on the biological barriers, represents a crucial aspect to be assessed in a nanosafety policy framework.Expand
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