• Publications
  • Influence
Remission of Goodpasture's syndrome after withdrawal of an unusual toxic.
A 19 year old girl working as a hairdresser developed a severe anemia due to occult pulmonary hemorrhage followed by anti-GBM glomerulonephritis with normal renal function. Withdrawal of theExpand
Immunological status of competitive football players during the training season.
A predominant neutrophil function depression in football players during a training season is suggested which could partly explain the susceptibility of elite athletes to infections. Expand
Tissue culture of normal rat glomeruli. Isolation and morphological characterization of two homogeneous cell lines.
The difference in the growth capacity of epithelial and smooth muscle-like cells allows their separate isolation by performing subcultures on day 6 for the former cells and on day 30 for the latter. Expand
Accumulation of several basement membrane proteins in glomeruli of patients with preeclampsia and other hypertensive syndromes of pregnancy. Possible role of renal prostaglandins and fibronectin.
Alterations in the metabolism of prostaglandins and the increased deposition of fibronectin observed during preeclampsia could play a pathogenic role in the accumulation of basement membrane proteins in glomeruli of pregnant hypertensive patients. Expand
Linear glomerular IgG fixation in renal allografts: incidence and significance in Alport's syndrome.
Twelve of 767 renal allograft recipients developed linear fixation of IgG along the glomerular basement membrane (GBM) by direct immunofluorescence technique and 5 had Alport's syndrome; the 7 others had various renal diseases, excluding anti-GBM nephritis. Expand
Uptake of Nanoparticles by Rat Glomerular Mesangial Cells in Vivo and in Vitro
It is demonstrated here that isobutylcyanoacrylate nanoparticles loaded with actinomycin D (ADNP) concentrate in rat mesangial cells in vitro and in vivo, as compared to the free drug (AD). Expand
Radioimmunologic method for detection of antitubular basement membrane antibodies.
It was found that the sera of 2 patients out of 15 presenting with lupus nephritis contained a significant anti-TBM-binding activity, mainly directed against the noncollagenous material of TBM. Expand
Acute experimental glomerulonephritis induced by the glomerular deposition of circulating polymeric IgA-concanavalin A complexes.
The data indicate that performed polymeric IgA-ConA complexes can specifically bind to glomerular structures in vivo and trigger acute glomerulonephritis locally, analogous to those observed in someglomerular diseases associated with a cryoglobulinaemia. Expand
The high lectin-binding capacity of human secretory IgA protects nonspecifically mucosae against environmental antigens.
The anti-infectious role of human milk may be, at least partly, ascribed to its content in secretory IgA. As lectins are present in various infectious antigens, the binding of different types of IgAExpand
Possible pathogenic role of IgE in Henoch-Schönlein purpura
Investigation of the incidences of clinical and biological markers of atopy in children with IgA nephropathy and with Henoch-Schönlein purpura nephritis found immunoallergy might account, in some cases, for the cutaneous, intestinal and pulmonary signs observed in HSPN, but not in IgAN. Expand