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- Publications
- Influence
Prevalence of the mutation C677 --> T in the methylene tetrahydrofolate reductase gene among distinct ethnic groups in Brazil.
- V. Arruda, L. Siqueira, +5 authors F. Costa
- Biology, Medicine
- American journal of medical genetics
- 24 July 1998
Vascular disease is a serious public health problem in the industrialized world, and is a frequent cause of death among the adult population of Brazil. Mild hyperhomocysteinemia has been identified… Expand
The mutation Ala677-->Val in the methylene tetrahydrofolate reductase gene: a risk factor for arterial disease and venous thrombosis.
- V. Arruda, P. M. von Zuben, L. C. Chiaparini, J. Annichino-Bizzacchi, F. Costa
- Medicine
- Thrombosis and haemostasis
- 1 May 1997
Mild hyperhomocysteinemia has been identified as a risk factor for arterial disease and for venous thrombosis. Individuals homozygous for the thermolabile variant of the methylene tetrahydrofolate… Expand
Very low incidence of Arg506-->Gin mutation in the factor V gene among the Amazonian Indians and the Brazilian black population.
- V. Arruda, P. M. von Zuben, M. Soares, R. Menezes, J. Annichino-Bizzacchi, F. Costa
- Biology, Medicine
- Thrombosis and haemostasis
- 27 February 1996
Rapid detection of factor V Leiden (FVQ506) by non-radioactive single strand conformation polymorphism (SSCP).
- V. Arruda, P. M. von Zuben, J. Annichino-Bizzachi, F. Costa
- Chemistry, Medicine
- Sangre
- 1 October 1996
The transition G-->A at position 506 of the factor V gene is responsible for resistance to the anticoagulant effect of activated protein C (APC-resistance), and represents the most common hereditary… Expand