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C‐terminal truncation of the transcriptional activator encoded by areA in Aspergillus nidulans results in both loss‐of‐function and gain‐of‐function phenotypes
Mutations truncating as many as 143 C‐terminal residues from the transcriptional activator encoded by the areA gene, mediating nitrogen metabolite repression in Aspergillus nidulans, do notExpand
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Studies pertaining to the purification and properties of thymine 7-hydroxylase.
Abstract 1. 1. It has been shown that the thymine 7-hydroxylase activity of cell-free extracts prepared from cultures of Neurospora crassa, grown under forced aeration in liquid media, is usuallyExpand
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Metabolism of pyrimidine deoxyribonucleosides in Neurospora crassa.
The experiments in this report involve the following series of reactions which were previously demonstrated with purified enzyme preparations from Neurospora crassa: thymidine a yields thymineExpand
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Regulation of thymidine metabolism in Neurospora crassa.
The utilization of thymidine by Neurospora crassa is initiated by the pyrimidine deoxyribonucleoside 2'-hydroxylase reaction and the consequent formation of thymine and ribose. Thymine must then beExpand
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The cell-free conversion of a deoxyribonucleoside to a ribonucleoside without detachment of the deoxyribose.
Abstract A cell-free preparation has been obtained from Neurospora crassa which catalyzes the conversion of thymidine to thymine riboside. This oxidation occurs at the deoxyribonucleoside level andExpand
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Substrate specificity of the hydroxylase reaction in which thymidine is converted to thymine ribonucleoside.
Abstract 1. 1.|A partially purified enzyme preparation from Neurospora crassa, which had previously been reported to convert thymidine to thymine ribonucleoside, catalyzes the conversion ofExpand
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C‐terminal truncation of the transcriptional activator encoded by area in Aspergillus nidulans results in both loss‐of‐function and gain‐of‐function phenotypes
Mutations truncating as many as 143 C-terminal residues from the transcriptional activator encoded by the areA gene, mediating nitrogen metabolite repression in Aspergillus nidulans, do notExpand
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Separation and characterization of pyrimidine deoxyribonucleoside 2'-hydroxylase and thymine 7-hydroxylase from Aspergillus nidulans.
Partially purified preparations from Aspergillus nidulans were shown to catalyze two alpha-ketoglutarate dependent dioxygenase reactions: the pyrimidine deoxyribonucleoside 2'-hydroxylase (ECExpand
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Regulation of pyrimidine salvage in Aspergillus nidulans: A role for the major regulatory gene areA mediating nitrogen metabolite repression
SummaryThe synthesis of thymine 7-hydroxylase, an α-ketoglutarate dependent dioxygenase, is subject both to nitrogen metabolite repression and to oxygen repression, while synthesis of the otherExpand
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