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- Publications
- Influence
Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1
MACC1 (Metastasis Associated in Colon Cancer 1) is a key driver and prognostic biomarker for cancer progression and metastasis in a large variety of solid tumor types, particularly colorectal cancer… Expand
Uptake, biodistribution, and time course of naked plasmid DNA trafficking after intratumoral in vivo jet injection.
- W. Walther, T. Minow, R. Martin, I. Fichtner, P. M. Schlag, U. Stein
- Biology, Medicine
- Human gene therapy
- 15 June 2006
Nonviral jet injection is an applicable technology for in vivo gene transfer of naked DNA. However, little is known about the biodistribution and clearance of jet-injected DNA, or about its… Expand
Cell surface α2,6-sialylation affects adhesion of breast carcinoma cells
- Shaoqiang Lin, W. Kemmner, S. Grigull, P. M. Schlag
- Biology
- 15 May 2002
Abstract Tumor-associated alterations of cell surface glycosylation play a crucial role in the adhesion and metastasis of carcinoma cells. The aim of this study was to examine the effect of… Expand
S3-Guideline “Exocrine Pancreatic Carcinoma” 20071
- G. Adler, T. Seufferlein, +19 authors I. Kopp
- Medicine
- 1 May 2008
Multiphoton excitation and photodynamic activity of macromolecular derivatized mTHPC
- M. Schneider, G. Graschew, +4 authors P. M. Schlag
- Chemistry, Engineering
- BiOS
- 29 March 2000
Multiphoton excitation of photosensitizers in photodynamic therapy constitutes a promising approach, because of the increasing tissue penetration for longer wavelength of illumination. In this… Expand
Optical Characterization of Breast Tumors by Frequency-Domain Optical Mammography
- S. Fantini, S. Walker, +6 authors E. Gratton
- Medicine
- 8 March 1998
We present a method aimed at the non-invasive optical characterization of breast tumors. This method is based on using diffusion theory to model the propagation of intensity-modulated light in breast… Expand
Integrins and E-Cadherin Expression – A Way for the Better Understanding of the Biological Behaviour of Colorectal Cancer
- H. Terpe, C. Zörb, L. Finke, P. M. Schlag
- Biology
- 1 July 1997
Colorectal carcinoma ranks second in frequency among all malignant tumors in the developed industrial countries. Determination of tumor cell differentiation together with pathological and clinical… Expand
Active Specific Immunotherapy with Autologous Tumor Cell Vaccines Modified by Newcastle Disease Virus: Experimental and Clinical Studies
- V. Schirrmacher, P. Hoegen, +5 authors G. Bastert
- Medicine
- 1989
Active specific immunotherapy (ASI) procedures usually involve active vaccination with intact, but inactivated tumor cells or with tumor-derived subcellular membrane fractions. Such material is… Expand
Inhibition of Galβ1,4GlcNAc α2,6 sialyltransferase expression by antisense‐oligodeoxynucleotides
- W. Kemmner, Kathrin Hohaus, P. M. Schlag
- Biology
- 16 June 1997
Treatment of human colorectal carcinoma cells HT29 with specific antisense oligodeoxynucleotides led to a decreased Galβ1,4GlcNAc α2,6 sialyltransferase activity on the level of protein expression as… Expand
HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model
- T. Nguyen-Hoai, D. Kobelt, +8 authors J. Westermann
- Medicine
- Oncoimmunology
- 1 December 2012
DNA vaccines are potential tools for the induction of immune responses against both infectious disease and cancer. The dermal application of DNA vaccines is of particular interest since the epidermal… Expand