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Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult.
Judith Jacobi, PharmD, FCCM, BCPS; Gilles L. Fraser, PharmD, FCCM; Douglas B. Coursin, MD; Richard R. Riker, MD; Dorrie Fontaine, RN, DNSc, FAAN; Eric T. Wittbrodt, PharmD; Donald B. Chalfin, MD, MS,… Expand
The ECLIPSE Trials: Comparative Studies of Clevidipine to Nitroglycerin, Sodium Nitroprusside, and Nicardipine for Acute Hypertension Treatment in Cardiac Surgery Patients
BACKGROUND: Acute hypertension during cardiac surgery can be difficult to manage and may adversely affect patient outcomes. Clevidipine is a novel, rapidly acting dihydropyridine L-type calcium… Expand
Treatment of Acute Postoperative Hypertension in Cardiac Surgery Patients: An Efficacy Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery-2 (ESCAPE-2), a…
BACKGROUND: Acute postoperative hypertension is a well-known complication of cardiac surgery and is associated with postoperative morbidity. Clevidipine, an ultrashort-acting, third-generation… Expand
Emergence and Recovery Characteristics of Desflurane Versus Sevoflurane in Morbidly Obese Adult Surgical Patients: A Prospective, Randomized Study
- E. Strum, J. Szenohradszki, W. A. Kaufman, G. Anthone, Ingrid L Manz, P. Lumb
- Anesthesia and analgesia
- 1 December 2004
We compared postoperative recovery after desflurane (n = 25) versus sevoflurane (n = 25) anesthesia in morbidly obese adults (body mass index ≥35) who underwent gastrointestinal bypass surgery via an… Expand
Intravenous Lidocaine Speeds the Return of Bowel Function, Decreases Postoperative Pain, and Shortens Hospital Stay in Patients Undergoing Radical Retropubic Prostatectomy
Postoperative ileus is a concern among surgical patients.Epidural anesthesia and analgesia with local anesthetics can decrease the duration of ileus. Significant systemic absorption of local… Expand
A Comparison Between 25% Albumin and 6% Hydroxyethyl Starch Solutions on Lung Water Accumulation During and Immediately After Cardiopulmonary Bypass
- P. Lumb
- Annals of surgery
- 1 August 1987
Six per cent hydroxyethyl starch was compared prospectively with 25% albumin as the oncotic component of cardiopulmonary pump prime solutions. Oncotic pressure of the pump prime solution was… Expand
Does Perioperative Systolic Blood Pressure Variability Predict Mortality After Cardiac Surgery? An Exploratory Analysis of the ECLIPSE trials
BACKGROUND: Few studies describe an association of perioperative blood pressure stability with postoperative outcome. We tested the hypothesis that systolic blood pressure (SBP) variability in… Expand
Are giant ganglia a reliable marker of intestinal neuronal dysplasia type B (IND B)?
Abstract It has been suggested that giant ganglia are a marker for a developmental bowel disorder, intestinal neuronal dysplasia of the submucosal plexus (IND B), diagnosed in a proportion of… Expand
Parenteral clevidipine for the acute control of blood pressure in the critically ill patient: a review
- W. Peacock, Jorge E Angeles, Karina M Soto, P. Lumb, J. Varon
- Therapeutics and clinical risk management
- 3 August 2009
Clevidipine is a new calcium channel blocker of the dihydropyridine class that is characterized by its ultra-short onset of action, vascular selectivity, small volume of distribution and extremely… Expand
Central vs peripheral venous catheters in critically ill patients.
A prospective study of 2,209 intravenous catheters was performed in a multidisciplinary intensive care unit to determine when and why catheters were removed and which sites of insertion were… Expand