• Publications
  • Influence
Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult.
Judith Jacobi, PharmD, FCCM, BCPS; Gilles L. Fraser, PharmD, FCCM; Douglas B. Coursin, MD; Richard R. Riker, MD; Dorrie Fontaine, RN, DNSc, FAAN; Eric T. Wittbrodt, PharmD; Donald B. Chalfin, MD, MS,Expand
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The ECLIPSE Trials: Comparative Studies of Clevidipine to Nitroglycerin, Sodium Nitroprusside, and Nicardipine for Acute Hypertension Treatment in Cardiac Surgery Patients
BACKGROUND: Acute hypertension during cardiac surgery can be difficult to manage and may adversely affect patient outcomes. Clevidipine is a novel, rapidly acting dihydropyridine L-type calciumExpand
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Treatment of Acute Postoperative Hypertension in Cardiac Surgery Patients: An Efficacy Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery-2 (ESCAPE-2), a
BACKGROUND: Acute postoperative hypertension is a well-known complication of cardiac surgery and is associated with postoperative morbidity. Clevidipine, an ultrashort-acting, third-generationExpand
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Emergence and Recovery Characteristics of Desflurane Versus Sevoflurane in Morbidly Obese Adult Surgical Patients: A Prospective, Randomized Study
We compared postoperative recovery after desflurane (n = 25) versus sevoflurane (n = 25) anesthesia in morbidly obese adults (body mass index ≥35) who underwent gastrointestinal bypass surgery via anExpand
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Intravenous Lidocaine Speeds the Return of Bowel Function, Decreases Postoperative Pain, and Shortens Hospital Stay in Patients Undergoing Radical Retropubic Prostatectomy
Postoperative ileus is a concern among surgical patients.Epidural anesthesia and analgesia with local anesthetics can decrease the duration of ileus. Significant systemic absorption of localExpand
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A Comparison Between 25% Albumin and 6% Hydroxyethyl Starch Solutions on Lung Water Accumulation During and Immediately After Cardiopulmonary Bypass
  • P. Lumb
  • Medicine
  • Annals of surgery
  • 1 August 1987
Six per cent hydroxyethyl starch was compared prospectively with 25% albumin as the oncotic component of cardiopulmonary pump prime solutions. Oncotic pressure of the pump prime solution wasExpand
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Does Perioperative Systolic Blood Pressure Variability Predict Mortality After Cardiac Surgery? An Exploratory Analysis of the ECLIPSE trials
BACKGROUND: Few studies describe an association of perioperative blood pressure stability with postoperative outcome. We tested the hypothesis that systolic blood pressure (SBP) variability inExpand
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Are giant ganglia a reliable marker of intestinal neuronal dysplasia type B (IND B)?
Abstract It has been suggested that giant ganglia are a marker for a developmental bowel disorder, intestinal neuronal dysplasia of the submucosal plexus (IND B), diagnosed in a proportion ofExpand
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Parenteral clevidipine for the acute control of blood pressure in the critically ill patient: a review
Clevidipine is a new calcium channel blocker of the dihydropyridine class that is characterized by its ultra-short onset of action, vascular selectivity, small volume of distribution and extremelyExpand
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Central vs peripheral venous catheters in critically ill patients.
A prospective study of 2,209 intravenous catheters was performed in a multidisciplinary intensive care unit to determine when and why catheters were removed and which sites of insertion wereExpand
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