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Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporter.
- J. E. Race, Fadi N Makhlouf, P. Logue, F. H. Wilson, P. Dunham, E. J. Holtzman
- Biology, Medicine
- American journal of physiology. Cell physiology
- 1 December 1999
We isolated and characterized a novel K-Cl cotransporter, KCC3, from human placenta. The deduced protein contains 1,150 amino acids. KCC3 shares 75-76% identity at the amino acid level with human,… Expand
Swelling activation of K-Cl cotransport in LK sheep erythrocytes: a three-state process
- P. Dunham, J. Klimczak, P. Logue
- Chemistry, Medicine
- The Journal of general physiology
- 1 May 1993
K-Cl cotransport in LK sheep erythrocytes is activated by osmotic swelling and inhibited by shrinkage. The mechanism by which changes in cell volume are transduced into changes in transport was… Expand
Cloning, characterization, and gene organization of K-Cl cotransporter from pig and human kidney and C. elegans.
- E. J. Holtzman, S. Kumar, +7 authors P. Dunham
- Biology, Medicine
- American journal of physiology. Renal physiology
- 1 October 1998
We isolated and characterized the cDNAs for the human, pig, and Caenorhabditis elegansK-Cl cotransporters. The pig and human homologs are 94% identical and contain 1,085 and 1,086 amino acids,… Expand
Passive potassium transport in LK sheep red cells. Modification by N- ethyl maleimide
- P. Logue, C. Anderson, C. Kanik, B. Farquharson, P. Dunham
- Chemistry, Medicine
- The Journal of general physiology
- 1 June 1983
Passive K transport, as modified by N-ethyl maleimide (NEM), was studied in erythrocytes of the low-K (LK) phenotype of sheep. Brief (5- min) treatment with NEM at less than 0.5 mM caused inhibition… Expand
Anion-dependent cation transport in erythrocytes.
- J. Ellory, P. Dunham, P. Logue, G. Stewart
- Chemistry, Medicine
- Philosophical transactions of the Royal Society…
- 1 December 1982
A selective survey of the literature reveals at least three major anion-dependent cation transport systems, defined as Na+ + Cl-, K+ + Cl- and Na+ + K+ + Cl- respectively. In human red cells, kinetic… Expand
Potassium-chloride cotransport in resealed human red cell ghosts.
Furosemide-inhibitable K influx is threefold higher in resealed ghosts of human erythrocytes than in intact cells. The enhancement is specific for K in that furosemide-inhibitable Na influx is the… Expand
The Post-Medieval Archaeology of Ireland, 1550-1850
- A. Horning, R. O'Baoill, C. Donnelly, P. Logue
- History
- 1 December 2007
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Extracellular Na+ inhibits Na+/H+ exchange: cell shrinkage reduces the inhibition.
- P. Dunham, S. J. Kelley, P. Logue
- Chemistry, Medicine
- American journal of physiology. Cell physiology
- 1 August 2004
Na+/H+ exchangers (NHE) are ubiquitous transporters participating in regulation of cell volume and pH. Cell shrinkage, acidification, and growth factors activate NHE by increasing its sensitivity to… Expand
Molecular cloning and functional characterization of KCC 3 , a new KCl cotransporter
JOANNE E. RACE,1 FADI N. MAKHLOUF,1,2 PAUL J. LOGUE,2 FREDERICK H. WILSON,3 PHILIP B. DUNHAM,2 AND ELI J. HOLTZMAN1,4 1Renal Division, Department of Medicine, and 4Department of Biochemistry and… Expand
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Stimulation of the Na/K pump in LK sheep erythrocytes by immunoglobulin fragments.
- R. Bratcher, C. Kanik-Ennulat, P. Logue, P. Dunham
- Biology, Medicine
- Immunological communications
- 1983
Alloimmune antiserum against the L antigen of red cells from sheep of the LK phenotype is known to stimulate by several fold active Na/K transport in LK cells. We have shown that monomeric fragments,… Expand
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