P. Little

Publications28
h-index7
Citations128
Highly Influential Citations2
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The induction of methaemoglobinemia as an adjunct to therapy for tabun poisoning.
The protective and therapeutic effectiveness of p-aminopropiophenone (PAPP) against tabun poisoning in the rat has been examined. The relationship between dosage of PAPP and percentage of methaemog...
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Know Why You Believe
In 2006, Christianity Today voted this title to be one of the top 50 books that have shaped evangelicals! This was also associate professor of, science and basic christianity for the dead maybe.… Expand
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Cholinolytics in the treatment of anticholinesterase poisoning. II. Treatment of sarin poisoning with an oxime and various combinations of cholinolytic compounds.
Thirty-four cholinolytic compounds were screened for protective activity in mice and rats exposed to sarin. All compounds were examined at a dosage of 50 μmoles/kg in the presence of 30 mg/kg of N-...
  • 3
Oral prophylaxis for anticholinesterase poisoning.
A method of protection against poisoning by cholinesterase inhibitors involving the use of N-methyl pyridinium-2-aldoxime methanesulphonate (P-2-S) orally, prior to exposure to the anticholinestera...
  • 9
Cholinolytics in the treatment of anticholinesterase poisoning. I. The effectiveness of certain cholinolytics in combination with an oxime for treatment of sarin poisoning.
The protection to sarin poisoning afforded mice by treatment with N-methylpyridinium-2-aldoxime methanesulphonate (P-2-S) in combination with each of 34 cholinolytic compounds used as substitutes for… Expand
  • 15
Oxime mixtures and atropine in the protection of mice and rats from sarin poisoning.
The protection provided by oral administration of mixtures of oximes prophylactically in conjunction with intramuscular atropine given therapeutically against sarin poisoning in the rat and mouse is… Expand
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CHOLINOLYTICS IN THE TREATMENT OF ANTICHOLINESTERASE POISONING. III. THE EFFECTS OF QUATERNIZATION AND ALTERATION OF ANIONIC FUNCTION OF THE POTENCY OF CHOLINOLYTICS IN THE TREATMENT OF SARIN…
Twenty-one quaternary ammonium salts of cholinolytic drugs have been assessed for potency against Sarin poisoning in mice and rats in a treatment using N-methylpyridinium-2-aldoxime methanesulphona...
  • 12
Cholinolytics in the treatment of anticholinesterase poisoning. IV. The effectiveness of five binary combinations of cholinolytics with oximes in the treatment of organophosphorus poisoning.
The selection, for use in combatting organophosphorus poisoning, of five binary cholinolytic drug combinations from previously screened compounds is described. Their effectiveness was determined in...
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E2--M1 ADMIXTURES OF TRANSITIONS IN $sup 68$Zn.
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THE INDUCTION OF METHEMOGLOBINEMIA AS AN ADJUNCT TO THERAPY FOR TABUN POISONING
The protective and therapeutic effectiveness of p-aminopropiophenone (PAPP) against tabun poisoning in the rat has been examined. The relationship between dosage of PAPP and percentage of… Expand
  • 2