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Expression of the Long Intergenic Non-Protein Coding RNA 665 (LINC00665) Gene and the Cell Cycle in Hepatocellular Carcinoma Using The Cancer Genome Atlas, the Gene Expression Omnibus, and
TLDR
Investigation of the expression of the long intergenic non-protein coding RNA 665 (LINC00665) gene and the cell cycle in hepatocellular carcinoma found it may be involved in the regulation of cell cycle pathways in HCC through ten identified hub genes.
Development of a prognostic index based on an immunogenomic landscape analysis of papillary thyroid cancer
TLDR
Together, the results screened several IRGs of clinical significance, revealed drivers of the immune repertoire, and demonstrated the importance of a personalized, IRG-based immune signature in the recognition, surveillance, and prognosis of PTC.
A circRNA–miRNA–mRNA network identification for exploring underlying pathogenesis and therapy strategy of hepatocellular carcinoma
TLDR
A combinative strategy of big data mining, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and computational biology was employed to dig HCC-related circRNAs and to explore their potential action mechanisms.
Ultrasound-Based Radiomics Analysis for Preoperatively Predicting Different Histopathological Subtypes of Primary Liver Cancer
TLDR
Ultrasound-based radiomics models can help distinguish histopathological subtypes of PLC and provide effective clinical decision making for the accurate diagnosis and treatment of P LC.
Prognostic Significance of LncRNA PVT1 and Its Potential Target Gene Network in Human Cancers: a Comprehensive Inquiry Based Upon 21 Cancer Types and 9972 Cases
TLDR
The level of PVT1 expression in tumor tissues was higher than in paired non-cancer tissues and was significantly associated with a poorer prognosis in cancer patients, suggesting that PVT 1 may serve as a potential biomarker associated with the progression and prognosis of human cancers.
Identification of down-regulated microRNAs in thyroid cancer and their potential functions.
TLDR
The genes identified here may act as a starting point for further investigation of the carcinogenic mechanisms of these miRNAs, and might influence tumorigenesis via critical pathways.
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