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DNA released from dying host cells mediates aluminum adjuvant activity
The finding that host DNA released from dying cells acts as a damage-associated molecular pattern that mediates alum adjuvant activity may increase the understanding of the mechanisms of action of current vaccines and help in the design of new adjuvants. Expand
Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice.
- D. Bedoret, H. Wallemacq, +16 authors F. Bureau
- Biology, Medicine
- The Journal of clinical investigation
- 1 December 2009
A crucial role for IMs is revealed in maintaining immune homeostasis in the respiratory tract and provides an explanation for the paradox that although airborne LPS has the ability to promote the induction of Th2 responses by lung DCs, it does not provoke airway allergy under normal conditions. Expand
The oxidant/antioxidant equilibrium in horses.
It is described how the oxidant/antioxidant equilibrium or oxidative stress can be evaluated in horses, and current knowledge about oxidative stress in equine medicine and equine exercise physiology is summarised. Expand
Acute phase proteins assessment for an early selection of treatments in growing calves suffering from bronchopneumonia under field conditions.
Blood samples were taken from calves with respiratory disease the first day of examination for determination of the serum concentration of haptoglobin, fibrinogen, alpha-2- and gamma-globulins, and albumin and these two proteins were useful for the identification of calves requiring an anti-inflammatory treatment. Expand
Heart rate, hematological and serum biochemical responses to show jumping
Detection of copy number variants in the horse genome and examination of their association with recurrent laryngeal neuropathy.
- M. Dupuis, Z. Zhang, K. Durkin, C. Charlier, P. Lekeux, M. Georges
- Biology, Medicine
- Animal genetics
- 1 April 2013
None of the 67 common CNVRs were significantly associated with RLN when accounting for multiple testing, however, a duplication on chromosome 10 was detected in 10 cases (representing three breeds and two unphenotyped parents but in none of the controls. Expand
Effect of show jumping on heart rate, blood lactate and other plasma biochemical values.
- T. Art, H. Amory, D. Desmecht, P. Lekeux
- Biology, Medicine
- Equine veterinary journal. Supplement
- 10 June 2010
The results of this study demonstrate that, although the speed and duration of such an exercise are low, show jumping represents a severe exertion which requires the use of anaerobic metabolism, which implies that the training schedule of jumpers must include power training in order to improve theirAnaerobic capacity. Expand
Sub-clinical diseases affecting performance in Standardbred trotters: diagnostic methods and predictive parameters.
Poor-performers had lower speeds at a blood lactate concentration of 4mmol/L (V(LA4)) and a heart rate of 200bpm on treadmill and racetrack, as well as lower values for haematological parameters, plasma angiotensin-converting enzyme and antioxidants, compared to control horses. Expand
The respiratory system: anatomy, physiology, and adaptations to exercise and training
Airborne dust and aeroallergen concentrations in different sources of feed and bedding for horses.
- S. Vandenput, L. Istasse, B. Nicks, P. Lekeux
- Environmental Science, Medicine
- The Veterinary quarterly
- 1 November 1997
Grass silages of approximately 50% dry matter and alfalfa pellets appeared to be very good sources of forage with low levels of dust and aeroallergens, and Supplements, such as whole grains and molassed concentrates, contained many respirable particles andAeroplastic particles, were significantly more dusty than good hay. Expand