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Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens
- L. Laureti, Lijiang Song, B. Aigle
- Biology, ChemistryProceedings of the National Academy of Sciences
- 28 March 2011
There is a constant need for new and improved drugs to combat infectious diseases, cancer, and other major life-threatening conditions. The recent development of genomics-guided approaches for novel…
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.
- F. Barona-Gómez, S. Lautru, F. Francou, P. Leblond, J. Pernodet, G. Challis
- Chemistry, BiologyMicrobiology
- 1 November 2006
TLDR
The Streptomyces lividans 66 chromosome contains a 1 MB deletogenic region flanked by two amplifiable regions
- M. Redenbach, F. Flett, J. Cullum
- BiologyMolecular and General Genetics MGG
- 1 November 1993
Genetic instability in Streptomyces species often involves large deletions sometimes accompanied by DNA amplification. Two such systems in Streptomyces lividans 66 involve the production of mutants…
Physical map of the Streptomyces lividans 66 genome and comparison with that of the related strain Streptomyces coelicolor A3(2)
- P. Leblond, M. Redenbach, J. Cullum
- BiologyJournal of bacteriology
- 1 June 1993
TLDR
Occurrence of deletions, associated with genetic instability in Streptomyces ambofaciens, is independent of the linearity of the chromosomal DNA
- G. Fischer, B. Decaris, P. Leblond
- BiologyJournal of bacteriology
- 1 July 1997
TLDR
The unstable region of Streptomyces ambofaciens includes 210 kb terminal inverted repeats flanking the extremities of the linear chromosomal DNA
- P. Leblond, G. Fischer, F. Francou, Franca Berger, M. Guérineau, B. Decaris
- BiologyMolecular microbiology
- 1 January 1996
TLDR
Evolution of the terminal regions of the Streptomyces linear chromosome.
- F. Choulet, B. Aigle, P. Leblond
- BiologyMolecular biology and evolution
- 1 December 2006
TLDR
Involvement of AlpV, a New Member of the Streptomyces Antibiotic Regulatory Protein Family, in Regulation of the Duplicated Type II Polyketide Synthase alp Gene Cluster in Streptomyces ambofaciens
- B. Aigle, Xiuhua Pang, B. Decaris, P. Leblond
- BiologyJournal of bacteriology
- 1 April 2005
ABSTRACT A type II polyketide synthase gene cluster located in the terminal inverted repeats of Streptomyces ambofaciens ATCC 23877 was shown to be responsible for the production of an orange pigment…
Diversity and Mobility of Integrative and Conjugative Elements in Bovine Isolates of Streptococcusagalactiae, S. dysgalactiae subsp. dysgalactiae, and S. uberis
- M. Haenni, E. Saras, Stéphane Bertin, P. Leblond, J. Madec, S. Payot
- Biology, MedicineApplied and Environmental Microbiology
- 15 October 2010
TLDR
New insights into the genetic instability of streptomyces.
- P. Leblond, B. Decaris
- BiologyFEMS microbiology letters
- 1 November 1994
TLDR
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