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Consensus statement for inert gas washout measurement using multiple- and single- breath tests
Recommendations are provided about these aspects, applicable to both the paediatric and adult testing environment, whilst outlining the important principles that are essential for the reader to understand.
European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia
This guideline focuses on clinical presentation, nasal nitric oxide, analysis of ciliary beat frequency and pattern by high-speed video-microscopy analysis, transmission electron microscopy, genotyping and immunofluorescence, and proposes a set of quality criteria for future research on the validity of diagnostic methods for primary ciliary dyskinesia.
Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease
It is shown that IL-8 promotes bacterial killing by neutrophils through CX CR1 but not CXCR2, which represents a new pathophysiologic mechanism in cystic fibrosis and other chronic lung diseases.
Impact of Sepsis on Neurodevelopmental Outcome in a Swiss National Cohort of Extremely Premature Infants
Proven sepsis significantly contributes to NDI in extremely preterm infants, independent of other risk factors, and better strategies aimed at reducing the incidence of Sepsis in this highly vulnerable population are needed.
High rhinovirus burden in lower airways of children with cystic fibrosis.
Impaired production of antiviral mediators may lead to the high RV burden in the lower airways of children with CF, and whether high RV load is a cause or a consequence of inflammation needs further investigation in longitudinal studies.
Clonal analysis of Inquilinus limosus isolates from six cystic fibrosis patients and specific serum antibody response.
- S. Schmoldt, P. Latzin, J. Heesemann, M. Griese, A. Imhof, M. Hogardt
- Biology, MedicineJournal of medical microbiology
- 1 October 2006
In conclusion, detection of I. limosus in the respiratory tract is accompanied by a specific serum antibody response and may reflect the infectious/pathogenic potential ofI.Limosus and may support the selective cultivation of this novel emerging pathogen.
α1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients
Although no effect on lung function was observed, the clear reduction of airway inflammation after α1-antitrypsin treatment may precede pulmonary structuralChanges in cystic fibrosis patients.
Air pollution during pregnancy and lung development in the child.
Normative data for lung function and exhaled nitric oxide in unsedated healthy infants
A large normative data set in unsedated infants offers reference values for future research and particularly for studies where sedation may put infants at risk, and highlights the impact of maternal and environmental risk factors on neonatal lung function.
Lung Volume, Breathing Pattern and Ventilation Inhomogeneity in Preterm and Term Infants
It is suggested that preterm infants with BPD have a high capacity to maintain functional lung volume during natural sleep and the alterations in breathing pattern with disease severity may reflect presence of adaptive mechanisms to cope with the disease process.