A clinicopathological study of autism.
A neuropathological study of autism was established and brain tissue examined from six mentally handicapped subjects with autism, finding the likely involvement of the cerebral cortex in autism.
The same prion strain causes vCJD and BSE
It is found that the biological and molecular transmission characteristics of vCJD are consistent with it being the human counterpart of BSE.
Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome)
Office of Rare Diseases Neuropathologic Criteria for Corticobasal Degeneration
Using neuropathologic criteria for corticobasal degeneration provides good differentiation of CBD from other tauopathies, except frontotemporal dementia and Parkinsonism linked to chromosome 17, where additional clinical or molecular genetic information is required to make an accurate diagnosis.
Preliminary NINDS neuropathologic criteria for Steele‐Richardson‐Olszewski syndrome (progressive supranuclear palsy)
We present the preliminary neuropathologic criteria for progressive supranuclear palsy (PSP) as proposed at a workshop held at the National Institutes of Health, Bethesda, MD, April 24 and 25, 1993.…
Validity and Reliability of the Preliminary NINDS Neuropathologic Criteria for Progressive Supranuclear Palsy and Related Disorders
- I. Litvan, J. Hauw, D. Anderson
- Medicine, PsychologyJournal of Neuropathology and Experimental…
- 1 January 1996
It was showed that with routine sampling and staining methods, neuropathologic examination alone was not fully adequate for differentiating the disorders and a clinicopathologic diagnostic criteria to improve on the NINDS criteria is proposed.
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.
- M. Spillantini, R. Crowther, R. Jakes, N. Cairns, P. Lantos, M. Goedert
- BiologyNeuroscience Letters
These findings provide an unexpected link between multiple system atrophy and Lewy body disorders and establish that alpha-synucleinopathies constitute a major class of human neurodegenerative disorder.
Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies
Neuropathological Diagnostic Criteria for Creutzfeldt‐Jakob Disease (CJD) and Other Human Spongiform Encephalopathies (Prion Diseases)
Neuropathological diagnostic criteria for Creutzfeldt‐Jakob disease (CJD) and other human transmissible spongiform encephalopathies (prion diseases) are proposed for the following disease entities:…
Decrease and structural modifications of phosphatidylethanolamine plasmalogen in the brain with Alzheimer disease.
- Z. Guan, Y. Wang, N. Cairns, P. Lantos, G. Dallner, P. Sindelar
- Biology, ChemistryJournal of neuropathology and experimental…
- 1 July 1999
Both the vinyl ether bond of phosphatidylethanolamine plasmalogen and polyunsaturated fatty acids are major targets in oxidative stress; thus, these specific lipid modifications strongly support the involvement of free radicals in the pathogenesis of AD.