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Comparative study of the anti-edematogenic effects of anethole and estragole.
BACKGROUND Anethole and estragole are monoterpene position isomers and constituents of essential oils from aromatic plants and were used in this study with the aim of analyzing theirExpand
Opioid‐like antinociceptive effects of oral administration of a lectin purified from the seeds of Canavalia brasiliensis
The objective of this study was to evaluate the antinociceptive effects of a lectin from Canavalia brasiliensis (ConBr) when administered orally to murine models of chemical and thermal nociception.Expand
Antiparasitic effect of Dinoponera quadriceps giant ant venom.
Neglected tropical diseases (NTD) are treated with toxic therapy of limited efficacy. Previously, we studied the antimicrobial effect of Dinoponera quadriceps venom (DqV) against bacteria. ToExpand
Venom's antinociceptive property in the primitive ant Dinoponera quadriceps.
ETHNOPHARMACOLOGICAL RELEVANCE In northeastern Brazil, Dinoponera (Ponerinae) ants macerate are used to treat ear ache and its sting, rheumatism, and back pain. Such a popular use is a relevant factExpand
Betulinic acid induces cell death by necrosis in Trypanosoma cruzi.
Chagas' disease is a neglected disease caused by the protozoan parasite Trypanosoma cruzi and constitutes a serious health problem worldwide. The treatment is limited, with variable efficacy ofExpand
Trypanocidal activity of polysaccharide extract from Genipa americana leaves.
ETHNOPHARMACOLOGICAL RELEVANCE The parts of the Genipa americana (Rubiaceae) tree, also known as "jenipapo" or "jenipapeiro", has been used in traditional Medicine in parasitic and bacterialExpand
Novel Pharmacological Properties of Dinoponera quadriceps Giant Ant Venom
The South American giant ant, Dinoponera quadriceps (Hymenoptera, Formicidae, Ponerinae), produces proteinaceous venom that has antinociceptive, neuroprotective and antimicrobial effects, therebyExpand
The acute inflammatory response induced in mice by the venom of the giant ant Dinoponera quadriceps involves macrophage and interleukin-1β.
Dinoponera quadriceps (Hymenoptera, Formicidae, Ponerinae) is a primitive and endemic ant of Northeastern Brazil, that uses its sting and associated venom gland to capture preys and for defense.Expand
Antiparasitic effect of (-)-α-bisabolol against Trypanosoma cruzi Y strain forms.
Chagas disease is caused by Trypanosoma cruzi and affects about 7 million people worldwide. Benznidazole and nifurtimox have low efficacy and high toxicity. The present study was designed to identifyExpand
Arabinogalactan-Glycoconjugate Fractions from Genipa americana Leaves as a Source of Antichagasic Natural Products
The extract from leaves of Genipa americana L., Rubiaceae, has antichagasic effect. The major components of this extract, arabinogalactan-glycoconjugate fractions (PFI and PFII), have shown similarExpand