• Publications
  • Influence
Electrogenic ion pumps
Electrogenic ion pumps convert chemical, reduction-oxidation, or light energy- into ion concentration differences across all living cells. They are the engines that run cells. In this text, Dr Lunger
Ion transport through pores: a rate-theory analysis.
  • P. Läuger
  • Chemistry, Medicine
    Biochimica et biophysica acta
  • 6 July 1973
This paper gives a treatment of ion transport through pores based on the theory of reaction rates, which allows for saturation effects in the pore, and shows that certain information on the single rate constants may be obtained from stationary conductance measurements.
Transport mechanism of hydrophobic ions through lipid bilayer membranes
SummaryEvidence is presented that the transport of lipid-soluble ions through bilayer membranes occurs in three distinct steps: (1) adsorption to the membranesolution interface; (2) passage over an
Electrical capacity of black lipid films and of lipid bilayers made from monolayers.
Planar bilayer membranes were formed from monolayers of a series of mono-unsaturated monoglycerides and lecithins and showed a negligible voltage dependence, whereas the Cm increased significantly at a voltage of 150 mV in the case of Mueller-Rudin-type monoolein films with n-decane as a solvent.
Formation of large, ion-permeable membrane channels by the matrix protein (porin) of Escherichia coli.
One of the major proteins of the outer membrane of Escherichia coli, the matrix protein (porin), has been isolated by detergent solubilisation and the findings are consistent with the assumption that the protein forms large aqueous channels in the membrane.
Transport phenomena in membranes.
  • P. Läuger
  • Chemistry, Medicine
    Angewandte Chemie
  • 1969
The investigation of theoretical membrane models has proved a valuable complement to the thermodynamic method and can now be rationally described with the aid of the thermodynamics of irreversible processes.
Electrical properties of bimolecular phospholipid membranes.
The electrical properties of bimolecular phospholipid membranes separating two aqueous electrolyte solutions were investivated and a steady membrane potential of nearly the limiting value was observed.
Effects of surface charge on the conductance of the gramicidin channel.
It is found that the electrostatic effect on the conductance is much larger for a neutral channel embedded in a negatively charged lipid than for the negatively charged O-pyromellityl analog (with three charges at the channel mouth) embedded inA neutral lipid.
Polarized infrared absorption of Na+/K+-ATPase studied by attenuated total reflection spectroscopy.
It is shown that Na+/K+-ATPase membrane fragments can be bound to a germanium plate coated with a phospholipid bilayer and about 24% of the NH-groups of the peptide backbone are found to be resistant to proton/deuterium exchange within a time period of several days.
Ionic selectivity of pores formed by the matrix protein (porin) of Escherichia coli.
Incorporation of the matrix protein (porin) from the outer membrane of Escherichia coli into black lipid films results in the formation of ion-permeable pores with a single-pore conductance of the