• Publications
  • Influence
Association of the VEGF gene polymorphism with diabetic retinopathy in type 2 diabetes patients.
BACKGROUND Diabetic microvascular complications are the major causes of morbidity and early mortality in diabetes. Vascular endothelial growth factor (VEGF) is a potent multifunctional cytokine whichExpand
  • 97
  • 8
Genetic polymorphisms of the renin-angiotensin system in end-stage renal disease.
BACKGROUND End-stage renal disease (ESRD) is a complex phenotype resulting from underlying kidney diseases of different etiologies as well as from environmental and genetic factors. The responsibleExpand
  • 77
  • 4
Interleukin-6 gene polymorphism and faster progression to end-stage renal failure in chronic glomerulonephritis.
Interleukin-6 (IL-6) is a multifunctional cytokine produced by different cell types, including monocytes, lymphocytes, endothelial and mesangial cells. Deregulated production of IL-6 was found to beExpand
  • 36
  • 2
Endothelial nitric oxide synthase gene intron 4 polymorphism in patients with end-stage renal disease.
BACKGROUND Nitric oxide (NO) synthesized by endothelial cell NO synthase (ecNOS) is a potent regulator of intrarenal haemodynamics. A polymorphism in intron 4 of the ecNOS gene is a candidate gene inExpand
  • 40
  • 2
The C677T methylenetetrahydrofolate reductase gene mutation and nephropathy in type 2 diabetes mellitus.
BACKGROUND Diabetic nephropathy is a common cause of end-stage renal disease, responsible for about 35% of renal replacement therapy cases. The susceptibility to nephropathy is due to environmentalExpand
  • 35
  • 2
Angiotensin II Type 1 Receptor Gene Polymorphism in End-Stage Renal Disease
The genes of the renin-angiotensin system (RAS) are involved in progression of renal failure. We examined the A1166C polymorphism at the angiotensin II type 1 (AT1R) locus in patients with end-stageExpand
  • 30
  • 2
M-charts as a tool for quantifying metamorphopsia in age-related macular degeneration treated with the bevacizumab injections
BackgroundThis article is aimed to assess quantitatively metamorphopsia using M-charts in patients suffering from wet age-related macular degeneration (AMD) treated with the intravitreal bevacizumabExpand
  • 24
  • 2
Interleukin-1 receptor antagonist gene polymorphism affects the progression of chronic renal failure.
End-stage renal disease (ESRD) involves an inflammatory process. Interleukin-1 receptor antagonist (IL-1Ra) and interleukin-1beta gene polymorphisms affect susceptibility to the disease in severalExpand
  • 21
  • 1
[Association of the renin-angiotensin system gene polymorphism with nephropathy in type II diabetes].
Diabetic nephropathy is the most frequent cause of end-stage renal failure. One of the crucial factors in a development of renal and cardiovascular complications of diabetes is geneticExpand
  • 14
  • 1
The effect of a single dialysis session on spatial QRS-T angle in haemodialysis patients.
BACKGROUND Abnormal values of the spatial angle between the directions of ventricular depolarization and repolarization (QRS-T) reflect the action potential inhomogeneities and predict cardiac eventsExpand
  • 10
  • 1
  • PDF