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Boron neutron capture therapy in the treatment of locally recurred head-and-neck cancer: final analysis of a phase I/II trial.
PURPOSE To investigate the efficacy and safety of boron neutron capture therapy (BNCT) in the treatment of inoperable head-and-neck cancers that recur locally after conventional photon radiationExpand
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L-boronophenylalanine-mediated boron neutron capture therapy for malignant glioma progressing after external beam radiation therapy: a Phase I study.
PURPOSE To investigate the safety of boronophenylalanine-mediated boron neutron capture therapy (BNCT) in the treatment of malignant gliomas that progress after surgery and conventional external beamExpand
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Boron neutron capture therapy in the treatment of locally recurred head and neck cancer.
PURPOSE Head and neck carcinomas that recur locally after conventional irradiation pose a difficult therapeutic problem. We evaluated safety and efficacy of boron neutron capture therapy (BNCT) inExpand
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Boron neutron capture therapy of brain tumors: clinical trials at the Finnish facility using boronophenylalanine
SummaryTwo clinical trials are currently running at the Finnish dedicated boron neutron capture therapy (BNCT) facility. Between May 1999 and December 2001, 18 patients with supratentorialExpand
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Metamorphosis of a 35 Year-Old TRIGA Reactor into a Modern BNCT Facility
Using FiR 1, a 250kW TRIGA reactor as a neutron source for BNCT was screened as a viable option in 1990, as the future of the reactor was questioned. By the initiative of the medical radio isotopeExpand
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Boron neutron capture therapy (BNCT) in Finland: technological and physical prospects after 20 years of experiences.
Boron Neutron Capture Therapy (BNCT) is a binary radiotherapy method developed to treat patients with certain malignant tumours. To date, over 300 treatments have been carried out at the Finnish BNCTExpand
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Boron Neutron Capture Therapy of Brain Tumors: Clinical Trials at the Finnish Facility Using Boronophenylalanine
Two clinical trials are currently running at the Finnish dedicated boron neutron capture therapy (BNCT) facility. Between May 1999 and December 2001, 18 patients with supratentorial glioblastoma wereExpand
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The alanine detector in BNCT dosimetry: dose response in thermal and epithermal neutron fields.
PURPOSE The response of alanine solid state dosimeters to ionizing radiation strongly depends on particle type and energy. Due to nuclear interactions, neutron fields usually also consist ofExpand
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MAGIC polymer gel for dosimetric verification in boron neutron capture therapy
Radiation‐sensitive polymer gels are among the most promising three‐dimensional dose verification tools developed to date. We tested the normoxic polymer gel dosimeter known by the acronym MAGICExpand
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