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Actual 10-year survival after resection of colorectal liver metastases defines cure.
- J. Tomlinson, W. Jarnagin, +7 authors M. D'angelica
- Journal of clinical oncology : official journal…
- 10 October 2007
PURPOSE Resection of colorectal liver metastases (CLM) in selected patients has evolved as the standard of care during the last 20 years. In the absence of prospective randomized clinical trials, a… Expand
Increased neutrophil-lymphocyte ratio is a poor prognostic factor in patients with primary operable and inoperable pancreatic cancer
Background:The neutrophil-lymphocyte ratio (NLR) has been proposed as an indicator of systemic inflammatory response. Previous findings from small-scale studies revealed conflicting results about its… Expand
Effect on Outcome of Recurrence Patterns After Hepatectomy for Colorectal Metastases
BackgroundDespite improvements in surgery and chemotherapy, most patients develop recurrence after hepatectomy for metastatic colorectal cancer. Data are lacking on the effect of these patterns on… Expand
Increased Use of Parenchymal-Sparing Surgery for Bilateral Liver Metastases From Colorectal Cancer Is Associated With Improved Mortality Without Change in Oncologic Outcome: Trends in Treatment Over…
Objective:The aim of this study was to determine the results of liver resection for patients with bilateral hepatic metastases from colorectal cancer. We aimed to assess the evolution of the… Expand
Lack of Evidence for Increased Operative Morbidity After Hepatectomy with Perioperative Use of Bevacizumab: A Matched Case-Control Study
BackgroundBevacizumab (bev) is a humanized monoclonal antibody that targets vascular endothelial growth factor (VEGF). Perioperative bev is now commonly used in patients undergoing hepatic resection.… Expand
MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance
Mucin glycoprotein expression can be altered during the carcinogenic process. The impact on the prognosis of patients with colorectal cancer (CRC) is controversial. We analyzed tumors from 381… Expand
Validation of C-reactive protein levels as a prognostic indicator for survival in a large cohort of pancreatic cancer patients
Background:Recent evidence indicates that the host inflammatory response has an important role in the tumour progression. Elevated C-reactive protein (CRP) levels have been previously associated with… Expand
Tumor necrosis is a new promising prognostic factor in colorectal cancer.
The prognostic significance of tumor necrosis in colorectal cancer is unclear. Our study aimed to analyze the prognostic value of tumor necrosis with respect to progression-free and cancer-specific… Expand
The elevated preoperative platelet to lymphocyte ratio predicts decreased time to recurrence in colon cancer patients.
BACKGROUND Recent evidence indicates that tumor progression involves factors of systemic inflammation, such as platelets and lymphocytes. In this study, we investigated the prognostic relevance of… Expand
Mucinous differentiation in colorectal cancer – indicator of poor prognosis?
Langner C, Harbaum L, Pollheimer M J, Kornprat P, Lindtner R A, Schlemmer A, Vieth M & Rehak P (2012) Histopathology 60, 1060–1072