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PRIMUS: a Windows PC-based system for small-angle scattering data analysis
A program suite for one-dimensional small-angle scattering data processing running on IBM-compatible PCs under Windows 9x/NT/2000/XP is presented and PRIMUS enables model-independent singular value decomposition or linear fitting if the scattering from the components is known. Expand
New developments in the ATSAS program package for small-angle scattering data analysis
The paper presents new developments and amendments to the ATSAS package (version 2.4) for processing and analysis of isotropic small-angle scattering data.
ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions
Developments and improvements of the ATSAS software suite (versions 2.5–2.8) for analysis of small-angle scattering data of biological macromolecules or nanoparticles are described.
ATSAS 2.1, a program package for small‐angle scattering data analysis
The program package ATSAS 2.1 for small-angle X-ray and neutron scattering data analysis is presented. The programs included in the package cover the major processing and interpretation steps fromExpand
Upgrade of the small-angle X-ray scattering beamline X33 at the European Molecular Biology Laboratory, Hamburg
The small-angle X-ray scattering beamline X33 of the European Molecular Biology Laboratory (EMBL) at the DORIS III storage ring [Deutsches Elektronen Synchrotron (DESY) Hamburg] was used for moreExpand
Structural bases for the interaction of frataxin with the central components of iron–sulphur cluster assembly
This study uses a combination of biophysical methods to define the structural bases of the interaction of CyaY (the bacterial orthologue of frataxin) with the IscS/IscU complex and suggests a new paradigm for understanding the role of fr ataxin as a regulator of IsCS functions. Expand
Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq
Bioinformatics, nuclear magnetic resonance spectroscopy, synchrotron radiation circular dichroism, and small angle X-ray scattering studies indicate that the C-termini are flexible and extend laterally away from the hexameric core, displaying features typical of intrinsically disordered proteins that facilitate intermolecular interactions. Expand
A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain
A mechanistic model based on freely jointed rigid segments that rationalizes the response to stretch of titin Ig-tandems according to molecular features is proposed and shows that conserved Ig–Ig transition motifs generate high-order in the structure of the filament. Expand
The Structure and Regulation of Human Muscle α-Actinin
The structure provides insight into the phosphoinositide-based mechanism controlling its interaction with sarcomeric proteins such as titin, lays a foundation for studying the impact of pathogenic mutations at molecular resolution, and is likely to be broadly relevant for the regulation of spectrin-like proteins. Expand
The peroxisomal receptor Pex19p forms a helical mPTS recognition domain
A divided N‐terminal and C-terminal structural arrangement in Pex19p is indicated, which is reminiscent of a similar division in the Pex5p receptor, to allow separation of cargo‐targeting signal recognition and additional functions. Expand